141939-07-3Relevant articles and documents
An unprecedented protocol for the synthesis of 3-hydroxy-3-phenacyloxindole derivatives with indolin-2-ones and α-substituted ketones
Bai, Mei,You, Yong,Chen, Yong-Zheng,Xiang, Guang-Yan,Xu, Xiao-Ying,Zhang, Xiao-Mei,Yuan, Wei-Cheng
, p. 1395 - 1401 (2016/02/03)
An unprecedented reaction between indolin-2-ones and α-substituted ketones has been developed. Using this protocol, a wide range of biologically important 3-hydroxy-3-phenacyloxindole derivatives could be obtained in good yield (up to 93%) under mild reaction conditions. A possible mechanism of this reaction was tentatively proposed based on some control experiments and MS spectrometry analysis.