148214-62-4 Usage
Description
1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy(9CI) is a heterocyclic organic compound characterized by a pyrrolopyrimidine ring with a methoxy group attached to the second carbon atom. It has the molecular formula C9H8N2O and is an important intermediate in the synthesis of various pharmaceuticals and biologically active compounds. This versatile chemical compound has a broad range of potential applications in the pharmaceutical industry, with its methoxy group playing a crucial role in modulating its physicochemical properties and pharmacological activities.
Uses
Used in Pharmaceutical Industry:
1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals and biologically active compounds. Its unique structure and methoxy group contribute to the development of new drugs with improved efficacy and selectivity.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy(9CI) serves as a valuable building block for the design and synthesis of novel drug candidates. Its versatile chemical properties allow for the creation of diverse molecular structures with potential therapeutic applications.
Used in Drug Development:
1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy(9CI) plays a significant role in drug development, as it can be utilized to create new chemical entities with potential therapeutic benefits. Its presence in the molecular structure can influence the compound's pharmacokinetics, pharmacodynamics, and overall drug performance.
Overall, 1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy(9CI) is a promising chemical compound with a wide range of applications in the pharmaceutical industry, medicinal chemistry, and drug development. Its unique structure and functional group make it an essential component in the creation of innovative and effective therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 148214-62-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,2,1 and 4 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 148214-62:
(8*1)+(7*4)+(6*8)+(5*2)+(4*1)+(3*4)+(2*6)+(1*2)=124
124 % 10 = 4
So 148214-62-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H7N3O/c1-11-7-9-4-5-2-3-8-6(5)10-7/h2-4H,1H3,(H,8,9,10)
148214-62-4Relevant articles and documents
Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents
Tung, Yen-Shih,Coumar, Mohane Selvaraj,Wu, Yu-Shan,Shiao, Hui-Yi,Chang, Jang-Yang,Liou, Jing-Ping,Shukla, Paritosh,Chang, Chun-Wei,Chang, Chi-Yen,Kuo, Ching-Chuan,Yeh, Teng-Kuang,Lin, Chin-Yu,Wu, Jian-Sung,Wu, Su-Ying,Liao, Chun-Chen,Hsieh, Hsing-Pang
supporting information; scheme or table, p. 3076 - 3080 (2011/06/25)
Utilizing scaffold-hopping drug-design strategy, we sought to identify a backup drug candidate for BPR0L075 (1), an indole-based anticancer agent. For this purpose, 5,6-fused bicyclic heteroaromatic scaffolds were designed and synthesized through shufflin
Anti-tumor compounds
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Page/Page column 13; 14, (2008/06/13)
Compounds of the following formula: wherein A, D, Q, T, U, V, W, X, Y, Z, R1, and ---- are as defined herein. This invention also relates to a method of inhibiting tubulin polymerization, or treating cancer or an angiogenesis-related disorder w
Synthesis of 2'-deoxyisoinosine and related 2'-deoxyribonucleosides
Seela,Chen,Bindig,Kazimierczuk
, p. 194 - 202 (2007/10/02)
Various 2-substituted purine and pyrrolo[2,3-d]pyrimidine 2'-deoxyribonucleosides with methylthio (13a), chloro (13b), methoxy (9b), and oxo (2, 3) substituents at C(2) are prepared. They are obtained either via stereoselective nucleobase-anion glycosylation or by base transformation. A three-step synthesis of the unknown 2'-deoxyisoinosine (2) from 2'-deoxyguanosine (15) is described. Compound 2 as well as its 7-deazapurine derivative 3 exhibit strong fluorescence.