15379-45-0

Basic information

• Product Name: 1,3-dihydro-3-ethyl-2H-indol-2-one
• Synonyms: 1,3-dihydro-3-ethyl-2H-indol-2-one;2H-Indol-2-one, 3-ethyl-1,3-dihydro-;3-ethylindolin-2-one;3-ethyl-1,3-dihydro-2H-Indol-2-one
• CAS NO: 15379-45-0
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161
• Mol File: 15379-45-0.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 292.7°C at 760 mmHg
• Flash Point: 168.3°C
• Appearance: /
• Density: 1.084g/cm³
• Vapor Pressure: 0.0018mmHg at 25°C
• Refractive Index: 1.539
• CAS DataBase Reference: 1,3-dihydro-3-ethyl-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dihydro-3-ethyl-2H-indol-2-one(15379-45-0)
• EPA Substance Registry System: 1,3-dihydro-3-ethyl-2H-indol-2-one(15379-45-0)

Safety Data

• Hazardous Substances Data: 15379-45-0(Hazardous Substances Data)

Usage

General Description

1,3-dihydro-3-ethyl-2H-indol-2-one is a chemical compound with the molecular formula C10H11NO. It is a cyclic organic compound that contains a five-membered ring with a nitrogen atom in the ring. It is often used as a building block in organic synthesis and pharmaceutical research. 1,3-dihydro-3-ethyl-2H-indol-2-one is known for its versatile reactivity and can be used to create a variety of different products. It is also used in the manufacture of pharmaceuticals, agrochemicals, and other specialty chemicals due to its unique structure and properties. Additionally, it has potential applications in the development of new drugs and therapeutic agents.

InChI:InChI=1/C10H11NO/c1-2-7-8-5-3-4-6-9(8)11-10(7)12/h3-7H,2H2,1H3,(H,11,12)

Upstream product

• 17266-70-5 3-Acetylindol-2-one 
• 201230-82-2 carbon monoxide 
• 73930-99-1 1-nitro-2-(prop-1-en-1-yl)benzene 
• 2597-29-7 3-ethylideneindolin-2-one 
• 59-48-3 2-oxoindole 
• 589-09-3 N-allyl-N-phenylamine 
• 32704-22-6 2-allyl-phenylamine 
• 1536478-63-3 (Z)-N-[2-(prop-1-enyl)phenyl]formamide 
• 1536478-59-7 (E)-N-[2-(prop-1-enyl)phenyl]formamide 
• 10113-38-9 N-(2-bromophenyl)formamide 
• 74-96-4 ethyl bromide 
• 91-56-5 indole-2,3-dione 
• 854950-78-0 3,3'-diethyl-3H,3'H-[3,3']biindolyl 
• 1484-19-1 3-ethyl-1H-indole 

Downstream Products

• 1484-19-1 3-ethyl-1H-indole 
• 1376933-28-6 (R)-3-ethyl-3-(phenylthio)indolin-2-one 
• 1393491-72-9 3-ethyl-3-(phenylthio)indolin-2-one 
• 1310861-58-5 (R)-3-ethyl-3-(hydroxy(phenyl)amino)indolin-2-one 

Relevant articles and documents

Iron-Catalyzed Borrowing Hydrogen C-Alkylation of Oxindoles with Alcohols

A general and efficient iron-catalyzed C-alkylation of oxindoles has been developed. This borrowing hydrogen approach employing a (cyclopentadienone)iron carbonyl complex (2 mol %) exhibited a broad reaction scope, allowing benzylic and simple primary and secondary aliphatic alcohols to be employed as alkylating agents. A variety of oxindoles underwent selective mono-C3-alkylation in good-to-excellent isolated yields (28 examples, 50–92 % yield, 79 % average yield).

Biocatalysed olefin reduction of 3-alkylidene oxindoles by baker's yeast

3-Substituted oxindoles are very interesting molecules both for their potential biological activity and for their role as starting materials toward more complex oxindole-based structures. These molecules can be prepared by the reduction of a 3-ylidene oxi

Evaluation of 3-ethyl-3-(phenylpiperazinylbutyl)oxindoles as PET ligands for the serotonin 5-HT7 receptor: Synthesis, pharmacology, radiolabeling, and in vivo brain imaging in pigs

We have investigated several oxindole derivatives in the pursuit of a 5-HT7 receptor PET ligand. Herein the synthesis, chiral separation, and pharmacological profiling of two possible PET candidates toward a wide selection of CNS-targets are de