1609939-41-4

Basic information

• Product Name: 2-methoxy-3-phenylbenzo[g]isoquinolin-1(2H)-one
• Synonyms: 2-methoxy-3-phenylbenzo[g]isoquinolin-1(2H)-one
• CAS NO: 1609939-41-4
• Molecular Weight: 301.345
• Mol File: 1609939-41-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-methoxy-3-phenylbenzo[g]isoquinolin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-3-phenylbenzo[g]isoquinolin-1(2H)-one(1609939-41-4)
• EPA Substance Registry System: 2-methoxy-3-phenylbenzo[g]isoquinolin-1(2H)-one(1609939-41-4)

Safety Data

• Hazardous Substances Data: 1609939-41-4(Hazardous Substances Data)

Upstream product

• 76749-35-4 2-methoxy-3-phenylbenzo[g]isoquinolin-1(2H)-one 
• 20187-61-5 mesyloxyacetophenone 

Relevant articles and documents

Tunable Synthesis of 3-Hydroxylisoquinolin-1,4-dione and Isoquinolin-1-one Enabled by Copper-Catalyzed Radical 6- endo Aza-cyclization of 2-Alkynylbenzamide

In this work, switchable synthesis of isoquinolin-1-one and 3-hydroxylisoquinolin-1,4-dione from 2-alkynylbenzamide is reported. The transformation works well with good yields and a broad reaction scope. The synthetic switch for providing isoquinolin-1-one and 3-hydroxylisoquinolin-1,4-dione is enabled by the use of a N2 or O2 atmosphere. Mechanism studies show that the reaction proceeds in a regioselective manner via a N-center radical 6-endo-dig aza-cyclization pathway.