16188-57-1

Basic information

• Product Name: 2-iodo-4-methylphenol
• Synonyms: 2-iodo-4-methylphenol;p-Cresol, 2-iodo-
• CAS NO: 16188-57-1
• Molecular Formula: C₇H₇IO
• Molecular Weight: 234.03435
• Mol File: 16188-57-1.mol
• Article Data: 48

Chemical Properties

• Melting Point: 35°C
• Boiling Point: 241.17°C (rough estimate)
• Appearance: /
• Density: 1.6840
• Refractive Index: 1.5331
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• PKA: 8.82±0.18(Predicted)
• Stability: Stench
• CAS DataBase Reference: 2-iodo-4-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-iodo-4-methylphenol(16188-57-1)
• EPA Substance Registry System: 2-iodo-4-methylphenol(16188-57-1)

Safety Data

• Hazardous Substances Data: 16188-57-1(Hazardous Substances Data)

Usage

General Description

2-Iodo-4-methylphenol, also known as 2-Iodo-4-methylphenol, is a chemical compound with the molecular formula C7H7IO. It is a derivative of phenol and is characterized by the presence of an iodo group and a methyl group on the aromatic ring. It is commonly used as an antiseptic and disinfectant in various pharmaceutical and healthcare products. Additionally, it exhibits antimicrobial properties, making it effective in controlling the growth of bacteria and fungi. 2-Iodo-4-methylphenol is also used in the production of dyes, pigments, and other industrial chemicals. However, it is important to handle this compound with caution, as it is toxic and can cause irritation to the skin, eyes, and respiratory system when handled improperly.

Upstream product

• 106-44-5 p-cresol 
• 1121-70-6 sodium 4-methylphenoxide 
• 7553-56-2 iodine 
• 95-84-1 3-amino-4-hydroxytoluene 
• 859821-79-7 4,4'-dimethyl-2,2'-selanediyl-di-phenol 
• 10034-85-2 hydrogen iodide 
• 2432-18-0 2,6-diiodo-4-methylphenol 
• 32707-05-4 thallium p-cresolate 

Downstream Products

• 121247-92-5 2-(2-hydroxy-5-methylphenylthio)benzoic acid 
• 2037-99-2 3-benzyl-2H-benzo[e][1,3]oxazine-2,4(3H)-dione 
• 99-50-3 3,4-Dihydroxybenzoic acid 
• 1123847-35-7 4-(2-iodo-4-methylphenoxymethyl)thiophene-2-carboxaldehyde 
• 1152781-28-6 C₁₀H₁₀O₂ 
• 1195764-61-4 6-methyl-4-phenyl-(2H)-1,4-benzoxazin-3(4H)-one 
• 39522-26-4 6-methyl-4H-benzo[1,4]oxazin-3-one 
• 1223462-93-8 2-(4-methyl-2-(2-phenylethynyl)phenoxy)-1-phenylethanone 
• 1309774-35-3 C₁₃H₁₆O 
• 1117722-84-5 C₁₇H₁₆O₂ 
• 40724-10-5 2-Styryl-5-methyl-benzo-furan 
• 22772-29-8 5-methyl-2-(4-methylphenyl)benzofuran 
• 19803-10-2 2-(4-methoxyphenyl)-5-methylbenzo[b]furan 
• 1117722-89-0 C₁₅H₁₁ClO 

Relevant articles and documents

A mild and simple regioselective iodination of activated aromatics with iodine and catalytic ceric ammonium nitrate

Molecular iodine in the presence of a catalytic amount of CAN has been utilized efficiently for regioselective iodination of activated aromatic compounds under mild reaction conditions.

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A novel and efficient domino process has been developed for the synthesis of 1,4-benzoxazepine derivatives from a range of readily accessible N-tosylaziridines, 2-iodophenols and isocyanides. This process involves the aziridine ring-opening reaction with 2-iodophenol, followed by a palladium-catalyzed isocyanide-insertion reaction. This regioselective and high-yielding transformation could be extended to its application for the synthesis of natural products and biologically interesting heterocycles. Copyright

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Biomimetic carbene cascades enabled imine derivative migration from carbene -bearing thiocarbamates

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