1667-10-3

Basic information

• Product Name: 4,4'-Bis(chloromethyl)-1,1'-biphenyl
• Synonyms: 4,4'-BIS(CHLOROMETHYL)-1,1'-BIPHENYL, 95 %;4,4'-bis(Chloromethyl)-1,1'-Bi;4,4-Dichloride-methyl-bispheny;BCMB 4,4-bis(Chloromethyl)-Biphenyl;4,4'-Bis(cnloromethyl)diphonyl;BCMP;4,4''-BIS(CHLOROMETHYL)-1,1''-BIPHENYL 95%;4,4'-bis(chloromethyl)-1,1'-biphenyl
• CAS NO: 1667-10-3
• Molecular Formula: C₁₄H₁₂Cl₂
• Molecular Weight: 251.15
• EINECS: 216-784-4
• Product Categories: Intermediates of Dyes and Pigments;Biphenyl & Diphenyl ether;Biphenyls (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;Aryl;C13 to C37+;Halogenated Hydrocarbons;Biphenyl series
• Mol File: 1667-10-3.mol
• Article Data: 14

Chemical Properties

• Melting Point: 126 °C (dec.)(lit.)
• Boiling Point: 184 °C / 0.2mmHg
• Flash Point: 196.3 °C
• Appearance: white to off-white powder
• Density: 1.195 g/cm³
• Vapor Pressure: 4.6Pa at 20℃
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: soluble in Tetrahydrofuran
• Water Solubility: 200ng/L at 20℃
• CAS DataBase Reference: 4,4'-Bis(chloromethyl)-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-Bis(chloromethyl)-1,1'-biphenyl(1667-10-3)
• EPA Substance Registry System: 4,4'-Bis(chloromethyl)-1,1'-biphenyl(1667-10-3)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 1667-10-3(Hazardous Substances Data)

Usage

Chemical Properties

White to light brown solid

Flammability and Explosibility

Notclassified

Upstream product

• 50-00-0 formaldehyd 
• 92-52-4 biphenyl 
• 7647-01-0 hydrogenchloride 
• 613-33-2 (4,4'-dimethyl-1,1'-biphenyl) 
• 75-15-0 carbon disulfide 
• 1667-12-5 4,4'-bis(hydroxymethyl)biphenyl 
• 542-88-1 bis(2-chloromethyl)ether 
• 787-70-2 4,4'-diphenic acid 

Downstream Products

• 17919-34-5 4,4'-bis(diethoxyphosphinylmethyl)biphenyl 
• 1268162-69-1 4,4'-bis(3-methylphenoxymethyl)-1,1'-biphenyl 
• 740810-41-7 4,4'-bis(tricyclohexyltinmethyl)biphenyl 
• 886212-15-3 4,4'-bis(5-(trichlorostannyl)butyloxymethyl)biphenyl 

Relevant articles and documents

Synthesis, antimicrobial and antifungal activity of double quaternary ammonium salts of biphenyls

The synthetic methods for new 2-, 2,2′-, and 3-substituted 4,4′-bis(chloromethyl)biphenyls were developed. Quaternization of them with various amines resulted in a series of new double quaternary ammonium salts containing the biphenyl moiety. The majority of the obtained compounds have a pronounced antifungal and antibacterial activity against the Gram-positive bacteria.

Method for preparing biphenyl benzyl dichloride through photocatalytic chlorination

The invention discloses a method for preparing biphenyl benzyl dichloride through photocatalytic chlorination. The method comprises the following steps: adding 4,4'-dimethyl biphenyl, a solvent and acatalyst into a reaction kettle, and carrying out stirring dissolution; turning on an ultraviolet lamp, and starting to introduce chlorine from the bottom; after 5 hours, monitoring the reaction process by gas chromatography, stopping the chlorine introducing when the total content of high-chlorinated products such as trichlorocompounds, tetrachlorocompounds and the like on the chromatography reaches 3%, continuously stirring for a certain time to expel residual chlorine, and then heating to evaporate out most of the solvent to obtain a crude product; and in the same reaction kettle, cooling the obtained crude product to below 40 DEG C, adding a solvent for recrystallization, continuously heating until the solvent is refluxed, completely dissolving the crude product, carrying out cooling crystallizing under stirring, filtering, and drying to obtain a white refined product.

A 4, 4' - dichloromethyl biphenyl preparation method

The invention discloses a production method of 4, 4'-bis (ehloromethyl) biphenyl. The production method comprises performing a chlorination reaction on 4, 4'-dimethyl biphenyl and a chlorination reagent under the action of an initiating agent and a free radical capture agent and performing after-treatment after the reaction is complete to obtain the 4, 4'-bis (ehloromethyl) biphenyl, wherein the structural formula of the 4, 4'-dimethyl biphenyl and the structural formula of the 4, 4'-bis (ehloromethyl) biphenyl are as follows. According to the production method of the 4, 4'-bis (ehloromethyl) biphenyl, raw materials which are low in price and easy to obtain are utilized, the target compound is obtained through the one-step reaction, and accordingly the cost is low, the operation is simple and convenient, the yield is high, the environment-friendly effect is achieved, and the production method is suitable for industrial production.