180028-21-1Relevant articles and documents
Synthesis and use of deuterated 3,4-dihydroxyphenylglycolaldehyde as an internal standard for determination of dopegal in brain tissue by gas chromatography-mass spectrometry
Li, Shu Wen,Spaziano, Vincent T.,Elliott, William H.,Burke, William J.
, p. 169 - 177 (2007/10/03)
Trideuterated 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL-d3) was synthesized from tetradeuterated catechol. After derivatization with N- methyl-N-trimethylsilyltrifluoroacetamide, the identity of DOPEGAL-d3 was confirmed by comparison with unlabeled DOPEGAL by gas chromatography-mass spectrometry (GC-MS); they have the same pattern of mass fragmentation. The deuterated DOPEGAL was used as an internal standard for the determination of DOPEGAL in human locus ceruleus by GC-MS in the selected ion monitoring mode.