18146-00-4Relevant articles and documents
Immobilization of biomolecules via ruthenium-catalyzed functionalization of the surface of silica with a vinylsilane
Hreczycho, Grzegorz,Chmielewski, Marcin K.,MacIejewski, Hieronim,Ratajczak, Tomasz,Marciniec, Bogdan
, p. 3605 - 3608 (2013)
A new ruthenium complex catalyzed procedure for the efficient O-silylation of an SiO-H group on the silica surface of glass beads with controlled pores (CPG) using 1-trimethylsiloxy-3-dimethylvinylsilylpropane leading to Si-O-Si bond formation with the evolution of ethylene is described. The formed linker contains alkyl hydroxyl groups which can be reacted with a nucleoside phosphoramidite unit. The CPG support containing alkyl hydroxyl groups is successfully applied in automatic chemical synthesis of DNA fragments.
Synthesis of bifunctional disiloxanes: Via subsequent hydrosilylation of alkenes and alkynes
Szyling, Jakub,Januszewski, Rafa?,Jankowska, Kamila,Walkowiak, J?drzej,Kownacki, Ireneusz,Franczyk, Adrian
, p. 4504 - 4507 (2021)
The first protocol for the synthesis of unsymmetrical bifunctional 1,1,3,3-tetramethyldisiloxane derivatives via subsequent hydrosilylation of alkenes and alkynes is presented. The methodology described has vast functional group tolerance and is extremely efficient towards the formation of novel disiloxane-based building blocks.
Room-Temperature Gold-Catalysed Arylation of Heteroarenes: Complementarity to Palladium Catalysis
Cresswell, Alexander J.,Lloyd-Jones, Guy C.
supporting information, p. 12641 - 12645 (2016/08/30)
Tailoring of the pre-catalyst, the oxidant and the arylsilane enables the first room-temperature, gold-catalysed, innate C?H arylation of heteroarenes. Regioselectivity is consistently high and, in some cases, distinct from that reported with palladium ca
Microwave-assisted synthesis of 1,3-bis(3-hydroxypropyl)-1,1,3,3-tetramethyldisiloxane
Cheng, Xitao,Li, Wenhong,Zhang, Cunshe,Huang, Fangfang,Wang, Qianjin,Zhou, Kui
, p. 567 - 571 (2016/01/20)
1,3-Bis(3-hydroxypropyl)-1,1,3,3-tetramethyldisiloxane was synthesized under microwave irradiation. The structure of the compound was analyzed by infrared spectroscopy, nuclear magnetic resonance hydrogen spectroscopy and gas chromatography. The optimal reaction condition was obtained by the single factor method. Under the optimal condition, the overall yield could reach 83.9 % and the purity of 1,3-bis(3-hydroxypropyl)-1,1,3,3-tetramethyldisiloxane was 99.1 %. It is found that under microwave radiation the reactions are very rapid with good yield, better quality and less time is required for the completion of the reaction.