18457-46-0 Usage
General Description
Taxinine J is a complex natural product from the taxine family, which is found in Taxus plants. It exhibits potent cytotoxic activity against cancer cell lines and is believed to interfere with microtubule dynamics, a key process in cell division. Taxinine J has a complex and unique chemical structure, featuring a tetracyclic core with multiple oxygen-containing functional groups, making it a challenging target for chemical synthesis. Due to its promising anti-cancer properties, Taxinine J has attracted significant interest from the scientific community as a potential lead compound for the development of new anti-cancer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 18457-46-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,5 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 18457-46:
(7*1)+(6*8)+(5*4)+(4*5)+(3*7)+(2*4)+(1*6)=130
130 % 10 = 0
So 18457-46-0 is a valid CAS Registry Number.
InChI:InChI=1/C37H46O10/c1-20-28-17-27-18-29(43-22(3)38)21(2)33(36(27,7)8)34(45-24(5)40)35(46-25(6)41)37(28,9)31(44-23(4)39)19-30(20)47-32(42)16-15-26-13-11-10-12-14-26/h10-16,27-31,34-35H,1,17-19H2,2-9H3/b16-15+
18457-46-0Relevant articles and documents
New taxanes from the needles of Taxus canadensis
Zhang,Sauriol,Mamer,Zamir, Lolita O.
, p. 929 - 933 (2007/10/03)
Nine minor taxanes were identified for the first time in the Canadian yew needles. Four of these metabolites are new: 5-epi-cinnamoylcanadensene (1), 2,9,10,13-tetraacetoxy-20-cinnamoyloxy-taxa-4(5),11(12)-diene (2), 2'-acetyl-epi-taxol (3), and 9-deacety