18598-31-7

Basic information

• Product Name: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, 4,4-dioxide
• CAS NO: 18598-31-7
• Molecular Formula: C16H18N2O6S
• Molecular Weight: 366.395
• Mol File: 18598-31-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, 4,4-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, 4,4-dioxide(18598-31-7)
• EPA Substance Registry System: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, 4,4-dioxide(18598-31-7)

Safety Data

• Hazardous Substances Data: 18598-31-7(Hazardous Substances Data)

Upstream product

• 99673-34-4 1,1-dioxo-6β-(2-phenyl-acetylamino)-1λ⁶-penicillanic acid cyanomethyl ester 
• 101522-53-6 1,1-dioxo-6β-(2-phenyl-acetylamino)-1λ⁶-penicillanic acid benzyl ester 
• 1254-56-4 benzyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 113-98-4 Penicillin G potassium 
• 61-33-6 penicillin G 

Downstream Products

• 121002-98-0 methoxymethyl benzylpenicillinate 1,1-dioxide 
• 71840-43-2 methyl 2-(2,4-dioxo-3-phenylacatamidoazetidin-1-yl)-3-methylbut-2-enoate 
• 121003-03-0 2-(2,4-dioxo-3-phenylacatamidoazetidin-1-yl)-3-methylbut-2-enoic acid 
• 121003-02-9 methoxymethyl 2-(2,4-dioxo-3-phenylacatamidoazetidin-1-yl)-3-methylbut-2-enoate 
• 121003-00-7 methoxymethyl 2-<(1R,5S)-3-benzyl-7-oxo-4-oxa-2,6-diazabicyclo<3.2.0>hept-2-en-6-yl>-3-methylbut-2-enoate 
• 121002-99-1 (2R,3S)-1-(1-methoxymethoxycarbonyl-2-methylprop-1-enyl)-4-oxo-3-phenylacetamidoazetidine-2-sulphinic acid 
• 121003-01-8 methoxymethyl 3-methyl-2-<(3R,4R)-2-oxo-3-phenylacetamido-4-pyruvoyloxyazetidin-1-yl>but-2-enoate 

Relevant articles and documents

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Process for preparing cephem lactones for cephalosporin-type antibiotics

Cephem lactones of formula (1) STR1 wherein R1 is hydrogen or an organic substituent of the type appearing as the 6-substituent of penicillins or as the 7-substituent of cephalosporins are produced from corresponding 4,5-halohydrin precursors thereof by dehalogenation. Novel stereoisomers of formula (1) compounds as well as novel intermediates for cephem lactone syntheses are disclosed. The cephem lactones produced according to the invention are of utility as intermediates for cephem-type antibiotics and have antibiotic properties of their own.