21865-76-9

Basic information

• Product Name: 4-phenylpentane-1,4-diol
• Synonyms: 4-phenylpentane-1,4-diol
• CAS NO: 21865-76-9
• Molecular Weight: 180.247
• Mol File: 21865-76-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-phenylpentane-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenylpentane-1,4-diol(21865-76-9)
• EPA Substance Registry System: 4-phenylpentane-1,4-diol(21865-76-9)

Safety Data

• Hazardous Substances Data: 21865-76-9(Hazardous Substances Data)

Upstream product

• 71-43-2 benzene 
• 2051-95-8 succinylbenzene 
• 5747-06-8 4-phenylpent-4-enoic acid 
• 93222-37-8 4-phenylpent-4-en-1-ol 
• 6712-35-2 2-phenylpent-4-yn-2-ol 
• 340184-74-9 1-(oxiran-2-yl)-2-phenylpropan-2-ol 
• 4743-74-2 2-phenylpent-4-en-2-ol 
• 98-86-2 acetophenone 
• 1071-73-4 5-Hydroxy-2-pentanone 

Downstream Products

• 28771-65-5 6-methyl-6-phenyltetrahydro-2H-pyran-2-one 

Relevant articles and documents

Cobalt-catalyzed oxidative cyclization of gem-disubstituted conjugated alkenols

Aryl gem-disubstituted conjugated alkenols underwent oxidative cyclization affording 2,5,5-trisubstituted tetrahydrofurans in reasonable yields and good diastereoselectivities using the reductive termination variation of the Mukaiyama aerobic oxidative reaction. Under oxidative termination, the same alkenols produced diols and ketonic by-products via the double hydration and beta-scission competing pathways. Furthermore, the differences in alkenol reactivity under the reductive and oxidative termination conditions were investigated.

SYNTHESE DE COMPOSES DIHYDRO-2,3 FURANNIQUES PAR HYDROBORATION D'ALCOOLS β-ACETYLENIQUES

Hydroboration of β acetylenic alcohols followed by NaOH/H2O2 oxidation leads to hemiacetals of γ aldols which are easily dehydrated to 2,3-dihydrofuran compounds.The reaction gives good yields with hindered alcohols and its stereochemistry may be controlled during the organometallic synthesis of the starting alcohol.