218916-52-0 Usage
Description
DIACETYL BENZOYL LATHYROL, also known as Lathyrol-3,15-diacetate-5-benzoate, is a chemical compound with potential applications in various industries, particularly in the pharmaceutical sector. It is characterized by its ability to induce apoptosis in certain types of cancer cells, making it a promising candidate for cancer treatment.
Uses
Used in Pharmaceutical Industry:
DIACETYL BENZOYL LATHYROL is used as an anticancer agent for its ability to induce apoptosis in lung cancer A549 cells through the mitochondrial pathway. This includes the loss of mitochondrial potential and release of cytochrome c, which contributes to the inhibition of tumor growth and progression.
Cytotoxicity
EFL3 of lathyrane diterpenoids showed potent cytotoxicity to A549 cells. Furthermore, EFL3 induced apoptosis of A549 cells through mitochondrial pathway with involvement of loss of ΔΨm, release of cytochrome c.
The cytotoxicity of EFL3 was determined by an MTT assay to evaluate its antitumor activity. The results showed that EFL3 inhibited cell proliferation in a concentration-dependent manner in A549 cells after 72 h treatment. The IC50 of EFL3 for A549 cells was 34.04 ± 3.99 μM. The data suggested that EFL3 exhibited potent cytotoxicity towards these cells.
The results showed that EFL3 showed more potent cytotoxicity to A549 cellsMolecules 2011, 16 3225 than EFL1 (P < 0.01).
Check Digit Verification of cas no
The CAS Registry Mumber 218916-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,8,9,1 and 6 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 218916-52:
(8*2)+(7*1)+(6*8)+(5*9)+(4*1)+(3*6)+(2*5)+(1*2)=150
150 % 10 = 0
So 218916-52-0 is a valid CAS Registry Number.