2299-73-2Relevant articles and documents
Rodda,Rogasch
, p. 3927 (1956)
Synthesis and antimicrobial activity of some new coumarin and dicoumarol derivatives
El-Metwally, Souad A.,Regal, Mohsen K. A.,Shaban, Safa S.
, (2020/01/22)
PTC reaction of coumarin derivative 1 with alkyl halides afforded C4 oxygen alkylation products 2a-d in appreciative yield, whereas with phenyl isothiocyanate gives the C3 addition product 4; also, one-pot three-component PTC reactio
Dihydrazone compound high in affinity with Abeta protein and Tau protein, derivative thereof, and applications of dihydrazone compound and derivative
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Paragraph 0029-0031; 0047-0049, (2019/05/15)
The invention provides a dihydrazone compound high in affinity with Abeta protein and Tau protein, a derivative thereof, and applications of the dihydrazone compound and the derivative. The structureof the dihydrazone compound is represented by formula I. The dihydrazone compound can be directly taken as a fluorescence probe used for detecting neurofibrillary tangles in vivo or in tissue samples;when the dihydrazone compound is adopted in nuclear medicine imaging, appropriate radioisotopes are needed for labeling. The dihydrazone compound is especially suitable to be used for diagnosis of neurodegenerative diseases, and diagnosis of patients with diseases with Abeta plaques including Alzheimer's disease.