37239-47-7 Usage
Description
Wilforgine, a dihydroagarofuran sesquiterpenoid and pyridine alkaloid with the chemical formula C41H47NO19, is an alkaloid derived from Tripterygium wilfordii Hook. It forms colorless plates from MeOH-Me2CO and is dextrorotatory with a specific rotation of [α]25/sup>D + 25° (Me2CO). Wilforgine is known for its lymphocyte immunosuppressive properties, as well as its anti-tumor and anti-inflammatory effects.
Uses
Used in Pharmaceutical Industry:
Wilforgine is used as a lymphocyte immunosuppressant for its anti-tumor and anti-inflammatory effects. It helps in modulating the immune system and has potential applications in the treatment of various cancers and inflammatory diseases.
Used in Research and Development:
Wilforgine is used for content determination, identification, and pharmacological experiments in the field of drug discovery and development. Its unique properties make it a valuable compound for studying its potential therapeutic effects and understanding its mechanisms of action.
Used in Traditional Medicine:
Wilforgine, being derived from Tripterygium wilfordii, has a history of use in traditional medicine. It is employed for its immunosuppressive, anti-tumor, and anti-inflammatory properties, which can be beneficial in the treatment of various ailments and conditions.
Biological activity
Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.
References
Beroza., J. Arner. Chern. Soc., 74, 1585 (1952)
Beroza., ibid, 75,44 (1953)
Check Digit Verification of cas no
The CAS Registry Mumber 37239-47-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,2,3 and 9 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 37239-47:
(7*3)+(6*7)+(5*2)+(4*3)+(3*9)+(2*4)+(1*7)=127
127 % 10 = 7
So 37239-47-7 is a valid CAS Registry Number.