449173-64-2Relevant articles and documents
Two new antifungal saponins from the Tibetan herbal medicine Clematis tangutica
Du, Zhizhi,Zhu, Na,Ze-Ren-Wang-Mu, Na,Shen, Yuemao
, p. 547 - 551 (2007/10/03)
Bioassay-guided fractionation of the ethanol extract of the aerial parts of Clematis tangutica led to the isolation of two new antifungal triterpene saponins. Their structures were determined to be 3-O-α-L-arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester (1) and 3-O-β-D-glucopyranosyl-(1→4)-α-L-arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester (2) on the basis of spectral data and chemical evidence. Inhibitory activities of the two saponins against seven fungal strains were evaluated. Compounds 1 and 2 showed evident antifungal activity (MIA ≈ 2.5 μg/disc) against Saccharomyces cerevisiae, similar to the positive control amphotericin B and ordinary activities (MIA ≈ 10 μg/disc) against Penicillium avellaneum UC-4376, Candida glabrata, Trichosporon beigelii and Pyricularia oryzae. Compound 2 is a better antifungal agent than compound 1 against most of the fungal strains that were tested.
Apioglycyrrhizin and araboglycyrrhizin, two new sweet oleanene-type triterpene oligoglycosides from the root of Glycyrrhiza inflata
Kitagawa,Sakagami,Hashiuchi,Zhou,Yoshikawa,Ren
, p. 551 - 553 (2007/10/02)
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Saponin and sapogenol. XL. Structure of sophoraflavoside I, a bisdesmoside of soyasapogenol B, from Sophorae radix, the root of Sophora flavescens Aiton
Yoshikawa,Wang,Kayakiri,et al.
, p. 4267 - 4274 (2007/10/02)
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