4497-05-6

Basic information

• Product Name: N-TETRADECANOPHENONE
• Synonyms: PHENYL N-TRIDECYL KETONE;N-TETRADECANOPHENONE;MYRISTOPHENONE;1-phenyl-1-tetradecanon;1-Phenyl-1-tetradecanone;1-Tetradecanone, 1-phenyl-;Ketone, phenyl tridecyl;Tridecyl phenyl ketone
• CAS NO: 4497-05-6
• Molecular Formula: C₂₀H₃₂O
• Molecular Weight: 288.47
• EINECS: 224-790-3
• Product Categories: Aromatic Ketones (substituted);C15 to C38;Carbonyl Compounds;Ketones
• Mol File: 4497-05-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: 46-52 °C(lit.)
• Boiling Point: 212 °C12 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 0.9262 (rough estimate)
• Vapor Pressure: 2.17E-05mmHg at 25°C
• Refractive Index: 1.4880 (estimate)
• CAS DataBase Reference: N-TETRADECANOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: N-TETRADECANOPHENONE(4497-05-6)
• EPA Substance Registry System: N-TETRADECANOPHENONE(4497-05-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 4497-05-6(Hazardous Substances Data)

Usage

Description

N-TETRADECANOPHENONE, also known as Tetradecanophenone, is an organic compound with the chemical formula C20H32O. It is a type of ketone derived from the separation of various phenones through hydrophobic interaction electrokinetic chromatography. N-TETRADECANOPHENONE is characterized by its unique chemical structure and properties, which make it suitable for various applications across different industries.

Uses

Used in Chemical Synthesis:
N-TETRADECANOPHENONE is used as an intermediate in the synthesis of various chemical compounds, such as pharmaceuticals, fragrances, and agrochemicals. Its unique chemical structure allows for the creation of a wide range of products with diverse applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-TETRADECANOPHENONE is used as a building block for the development of new drugs. Its chemical properties make it a valuable component in the synthesis of various therapeutic agents, contributing to the advancement of medical treatments.
Used in Cosmetics Industry:
N-TETRADECANOPHENONE is used as a key ingredient in the formulation of cosmetics, particularly in the creation of fragrances and perfumes. Its unique scent profile and stability make it an ideal candidate for use in the development of long-lasting and appealing fragrances.
Used in Research and Development:
N-TETRADECANOPHENONE is also utilized in research and development for the exploration of new chemical reactions and the discovery of novel compounds. Its unique properties make it a valuable tool for scientists and researchers in the field of organic chemistry.

InChI:InChI=1/C20H32O/c1-2-3-4-5-6-7-8-9-10-11-15-18-20(21)19-16-13-12-14-17-19/h12-14,16-17H,2-11,15,18H2,1H3

Upstream product

• 112-64-1 tetradecanoyl chloride 
• 71-43-2 benzene 
• 544-63-8 n-tetradecanoic acid 
• 65-85-0 benzoic acid 
• 629-63-0 myristonitrile 
• 16717-64-9 1-azidostyrene 
• 143-15-7 1-dodecylbromide 
• 936-59-4 3-chloropropiophenone 
• 112-53-8 1-dodecyl alcohol 
• 98-85-1 1-Phenylethanol 
• 98-86-2 acetophenone 
• 1733-58-0 phenacyldiphenylphosphine oxide 
• 4292-19-7 1-Iodododecane 
• 93-58-3 benzoic acid methyl ester 

Downstream Products

• 55850-73-2 p-tetradecylacetophenone 
• 55850-65-2 4-tetradecylbenzoic acid 
• 1411975-15-9 dimethyl (4R,5R)-2-phenyl-2-tridecyl-1,3-dioxolane-4,5-dicarboxylate 
• 1411975-16-0 diisopropyl (4R,5R)-2-phenyl-2-tridecyl-1,3-dioxolane-4,5-dicarboxylate 
• 1334474-74-6 C₂₂H₃₆O₂ 
• 1271732-52-5 (R)-1-phenyl-1-tetradecanol 
• 91323-12-5 4-tetradecylaniline 
• 1306630-57-8 C₆₀H₇₇N₅O₆ 
• 620180-59-8 C₂₆H₃₈N₂O 
• 1271732-57-0 (S)-1-phenyl-1-tetradecanol 
• 1221254-33-6 C₃₈H₆₂NO₂ 
• 1221254-34-7 C₃₈H₆₂NO₂ 
• 40489-75-6 C₁₈H₃₀NO 
• 1221254-31-4 C₃₈H₆₀NO₂ 

Relevant articles and documents

Vinyl Azides as Radical Acceptors in the Vitamin B12-Catalyzed Synthesis of Unsymmetrical Ketones

Vinyl azides are very reactive species and as such are useful building blocks, in particular, in the synthesis of N-heterocycles. They can also serve as precursors of ketones. These form in reactions of vinyl azides with nucleophiles or radicals. We have found, however, that under light irradiation vitamin B12 catalyzes the reaction of vinyl azides with electrophiles to afford unsymmetrical carbonyl compounds in decent yields. Mechanistic studies revealed that alkyl radicals are key intermediates in this transformation.

Mn-Enabled Radical-Based Alkyl-Alkyl Cross-Coupling Reaction from 4-Alkyl-1,4-dihydropyridines

Highly efficient alkylation of β-chloro ketones and their derivatives was achieved by means of domino dehydrochlorination/Mn-enabled radical-based alkyl-alkyl cross-coupling reaction. In situ-generated α,β-unsaturated ketones and their analogues were identified as the reaction intermediates. Known bioactive compounds, such as melperone and azaperone, could be easily prepared from β-chloropropiophenone in two steps.

Synthesis of new chiral and racemic 1,3-dioxolanes

A series of chiral 1,3-dioxolanes, 3-12, with >99% ee values, have been synthesized. This is the first study of chiral ketalization reaction starting from ketones with aryl, monosubstituted aryl, and long alkyl chains (C 11-AC13). Their ee values were determined by chiral high-performance liquid chromatography (HPLC) on Chiralcel OD column, using their racemic 1,3-dioxolanes rac-3-12, which were also synthesized for the first time. These chiral and racemic 1,3-dioxolanes were characterizated by infrared, NMR (1H, 13C), mass spectrometry, elemental analysis, optical rotation, and chiral HPLC.