54835-70-0Relevant articles and documents
A simple synthesis of four stereoisomers of roseoside and their inhibitory activity on leukotriene release from mice bone marrow-derived cultured mast cells
Yajima, Arata,Oono, Yutaka,Nakagawa, Ryusuke,Nukada, Tomoo,Yabuta, Goro
, p. 189 - 194 (2009)
Four stereoisomers of roseoside (vomifoliol glucosides) were synthesized using glucose as a chiral resolving reagent. The four synthetic stereoisomers exhibited inhibitory activity on leukotriene release from mouse bone marrow-derived cultured mast cells (BMCMC). The (6S)-isomers of roseoside were about twice as active as (6R)-isomers.
Synthesis of optically active vomifoliol and roseoside stereoisomers
Yamano, Yumiko,Ito, Masayoshi
, p. 541 - 546 (2007/10/03)
A synthesis of optically active vomifoliol stereoisomers 1-4 and their glucosides, roseoside stereoisomers 5-8, was accomplished via α-acetylenic alcohol 11a or 11b effectively prepared by an asymmetric transfer hydrogenation of α,β-acetylenic ketone 10. Simultaneous separation of these stereoisomers by HPLC was also perfomed.