588-68-1

Basic information

• Product Name: BENZALDEHYDE AZINE
• Synonyms: 1,4-Diphenyl-2,3-diaza-1,3-butadiene;2-(PhenylMethylene)hydrazone Benzaldehyde;NSC 3269;(1E,2E)-1,2-dibenzylidenehydrazine;benzoaldehyde azine;benzalazin;Benzaldazin;Benzaldazine
• CAS NO: 588-68-1
• Molecular Formula: C₁₄H₁₂N₂
• Molecular Weight: 208.26
• EINECS: 209-627-6
• Product Categories: Aromatics;Intermediates;Miscellaneous Reagents
• Mol File: 588-68-1.mol
• Article Data: 65

Chemical Properties

• Melting Point: 92-93 °C(lit.)
• Boiling Point: 318.3°Cat760mmHg
• Flash Point: 138.3°C
• Appearance: /
• Density: 0.98g/cm³
• Vapor Pressure: 0.000681mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: 0-10°C
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• PKA: 6.72±0.50(Predicted)
• BRN: 2208840
• CAS DataBase Reference: BENZALDEHYDE AZINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZALDEHYDE AZINE(588-68-1)
• EPA Substance Registry System: BENZALDEHYDE AZINE(588-68-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• RTECS: CU7571500
• TSCA: Yes
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• Hazardous Substances Data: 588-68-1(Hazardous Substances Data)

Usage

Description

BENZALDEHYDE AZINE is a pale yellow solid that is utilized in the synthesis of various symmetric and asymmetric azines, which possess a range of antibacterial and antifungal properties.

Uses

Used in Pharmaceutical Industry:
BENZALDEHYDE AZINE is used as a key intermediate for the synthesis of azines with antibacterial and antifungal activities. These azines are essential in the development of new drugs to combat resistant bacterial and fungal strains, addressing the growing need for effective treatments in the medical field.
Used in Chemical Research:
BENZALDEHYDE AZINE serves as a valuable compound in chemical research, particularly in the study of azine chemistry and its potential applications. Its synthesis and properties are of interest to researchers looking to understand the behavior of azines and their derivatives, which could lead to the discovery of new compounds with beneficial properties.

InChI:InChI=1/C14H12N2/c1-3-7-13(8-4-1)11-15-16-12-14-9-5-2-6-10-14/h1-12H

Upstream product

• 114198-89-9 {Ta(S-2,4,6-C6H2-i-Pr3)3(THF)}2(μ-N2) 
• 100-52-7 benzaldehyde 
• 916329-38-9 hydrogen azide 
• 6830-78-0 3,6-diphenyl-1,2,4,5-tetrazine 
• 14850-88-5 benzoylhydrazone of benzaldehyde 
• 13211-11-5 benzaldehyde benzylhydrazone 
• 555-96-4 Benzylhydrazine 
• 100-44-7 benzyl chloride 
• 114220-88-1 {Ta(O-2,6-C6H3-i-Pr2)3(THF)}2(μ-N2) 
• 5157-08-4 3-methyl-4,5-dihydro-6-oxopyridazine 
• 56-23-5 tetrachloromethane 
• 5281-18-5 benzaldehyde, hydrazone 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 100-47-0 benzonitrile 

Downstream Products

• 71284-90-7 N-[1-Phenyl-meth-(Z)-ylidene]-N'-[3,3,3-trifluoro-1-trifluoromethyl-prop-(E)-ylidene]-hydrazine 
• 93366-76-8 1,3,5-Triphenyl-4-benzylideneamino-1,2,4-Δ2-triazoline 
• 93366-77-9 1,5-Diphenyl-3-(4-nitrophenyl)-4-benzylideneamino-1,2,4-Δ2-triazoline 
• 24515-59-1 benzylidene-[2-phenyl-4-(2,2,2-trifluoro-1-trifluoromethyl-ethylidene)-[1,3]thiazetidin-3-yl]-amine 
• 114198-84-4 Ta(NNCHPh)(S-2,4,6-C₆H₂-i-Pr₃)3(THF) 
• 114198-82-2 Ta(NNCHPh)(O-2,6-C₆H₃-i-Pr₂)3(THF) 
• 23268-00-0 hydrazonium dibromide 
• 72068-86-1 bis(benzaldehyde azine)dichloropalladium(II) 
• 130691-47-3 cis-{V(CO)4C₆H₅CHN₂CHC₆H₅}^(1-) 
• 555-96-4 Benzylhydrazine 
• 1015074-06-2 C₂₆H₃₄N₄O₈S₂ 

Relevant articles and documents

Unexpected reaction of dibenzyl disulfide with hydrazine

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Ruthenium(ii)-catalysed 1,2-selective hydroboration of aldazines

Herein, an efficient and simple catalytic method for the selective and partial reduction of aldazines using ruthenium catalyst [Ru(p-cymene)Cl2]2 (1) has been accomplished. Under mild conditions, aldazines undergo the addition of pinacolborane in the presence of a ruthenium catalyst, which delivered N-boryl-N-benzyl hydrazone products. Notably, the reaction is highly selective, and results in exclusive mono-hydroboration and desymmetrization of symmetrical aldazines. Mechanistic studies indicate the involvement of in situ formed intermediate [{(η6-p-cymene)RuCl}2(μ-H-μ-Cl)] (1a) in this selective hydroboration.

Potassium tert -Butoxide Promoted Synthesis of 4,5-Diaryl-2 H -1,2,3-triazoles from Tosylhydrazones and Nitriles

Intermolecular cycloaddition of tosylhydrazones with nitriles was investigated. t -BuOK was shown to be an excellent base for increasing the effectiveness of the reaction in this protocol, and homocoupling of the tosylhydrazones was significantly inhibited by using xylene as a solvent. Through this transformation, a variety of 4,5-diaryl-2 H -1,2,3-triazoles were prepared in good to excellent yields and with high purities. The process is azide-free and transition-metal-free.