62025-48-3 Usage
Description
Bredinin 5'-monophosphate is a derivative of bredinin, a nucleoside antibiotic with cytotoxic and immunosuppressive properties. It selectively inhibits the activities of mammalian DNA polymerases in vitro, making it a potential candidate for various applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
Bredinin 5'-monophosphate is used as a cytotoxic and immunosuppressive agent for its ability to selectively inhibit mammalian DNA polymerases in vitro. This property makes it a promising candidate for the development of drugs targeting specific diseases and conditions.
Used in Anticancer Applications:
Bredinin 5'-monophosphate is used as an anticancer agent for its potential to inhibit the activities of mammalian DNA polymerases, which can help in the treatment of various types of cancer by disrupting the replication and transcription processes in cancer cells.
Used in Drug Development:
Bredinin 5'-monophosphate is used as a starting point for the development of new drugs with improved efficacy and reduced side effects. Its unique properties as a nucleoside antibiotic and inhibitor of DNA polymerases make it a valuable compound for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 62025-48-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,0,2 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 62025-48:
(7*6)+(6*2)+(5*0)+(4*2)+(3*5)+(2*4)+(1*8)=93
93 % 10 = 3
So 62025-48-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H14N3O9P/c10-7(15)4-8(16)12(2-11-4)9-6(14)5(13)3(21-9)1-20-22(17,18)19/h2-3,5-6,9,13-14,16H,1H2,(H2,10,15)(H2,17,18,19)/t3-,5-,6-,9-/m1/s1
62025-48-3Relevant articles and documents
Nucleosides and nucleotide. 145.1 synthesis of 2'-deoxy and 5'-phosphate derivatives of bredinin. A photochemical imidazole-ring cleavage and subsequent reconstruction of the base moiety
Shuto, Satoshi,Haramuishi, Kimiyo,Matsuda, Akira
, p. 187 - 190 (1996)
2'-Deoxy and 5'-phosphate derivatives of bredinin (2 and 3, respectively) were synthesized. UV irradiation of bredinin with a mercury lamp in aqueous HCl gave the imidazole-ring cleavage product 7 in high yield, which was converted to 2'-deoxy derivative
