621-27-2

Basic information

• Product Name: 3-N-PROPYLPHENOL
• Synonyms: 1-Hydroxy-3-n-propylbenzene;3-Propylphenol;3-propyl-phenol;m-Propylphenol;Phenol, m-propyl-;3-N-PROPYLPHENOL;META-PROPYLPHENOL;m-n-Propylphenol
• CAS NO: 621-27-2
• Molecular Formula: C₉H₁₂O
• Molecular Weight: 136.19
• EINECS: 210-675-5
• Mol File: 621-27-2.mol
• Article Data: 12

Chemical Properties

• Melting Point: 26°C
• Boiling Point: 229-231°C
• Flash Point: 229-231°C
• Appearance: /
• Density: 0.9870
• Vapor Pressure: 0.0451mmHg at 25°C
• Refractive Index: 1.5250
• Storage Temp.: 2-8°C
• PKA: 10.07±0.10(Predicted)
• Water Solubility: Soluble in water.
• CAS DataBase Reference: 3-N-PROPYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-N-PROPYLPHENOL(621-27-2)
• EPA Substance Registry System: 3-N-PROPYLPHENOL(621-27-2)

Safety Data

• Hazard Codes: C,Xn
• Statements: 20/21/22-36/37/38-34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3145
• WGK Germany: 3
• RTECS: SM8594000
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 621-27-2(Hazardous Substances Data)

Usage

Description

3-N-PROPYLPHENOL, also known as 3-n-propylphenol, is an organic compound with the molecular formula C9H12O. It is a liquid at room temperature and is characterized by its distinct chemical properties. 3-N-PROPYLPHENOL is primarily used as a precursor in the synthesis of various derivatives, which find applications in different industries.

Uses

Used in Chemical Synthesis:
3-N-PROPYLPHENOL is used as a precursor for the production of 2,4,5,6-tetrabromo-3-propylphenol. This synthesis process requires the use of reagents such as bromine and aluminum powder. The resulting compound, 2,4,5,6-tetrabromo-3-propylphenol, has potential applications in various fields, including pharmaceuticals and materials science.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-N-PROPYLPHENOL and its derivatives may be used as active ingredients or intermediates in the development of new drugs. 3-N-PROPYLPHENOL's unique chemical structure allows for the creation of novel molecules with potential therapeutic properties.
Used in Materials Science:
3-N-PROPYLPHENOL and its derivatives can also be utilized in the field of materials science, where they may be employed in the development of new materials with specific properties. These materials could have applications in various industries, such as electronics, coatings, and adhesives.

InChI:InChI=1/C9H12O/c1-2-4-8-5-3-6-9(10)7-8/h3,5-7,10H,2,4H2,1H3

Upstream product

• 2785-87-7 2-methoxy-4-n-propylphenol 
• 645-56-7 4-n-Propylphenol 
• 496-64-0 3-hydroxy-2-pyrone 
• 59807-91-9 1-Phenylsulfonyl-penten-⁽¹⁾ 
• 66022-60-4 1-nitropent-1-ene 
• 1415155-47-3 3-(non-8-enyl)phenol 
• 79755-53-6 1-(3-hydroxyphenyl)prop-1-ene 
• 62103-69-9 3-propylanisole 
• 2398-37-0 3-methoxyphenyl bromide 
• 874501-48-1 2-hydroxy-4-propyl-benzoic acid ethyl ester 
• 100-83-4 meta-hydroxybenzaldehyde 
• 1700-37-4 3-Benzyloxybenzaldehyde 
• 74-85-1 ethene 
• 108-39-4 3-methyl-phenol 

Downstream Products

• 32749-00-1 4-chloro-3-propylphenol 
• 532966-03-3 2-hydroxy-4-propylbenzaldehyde 
• 891859-12-4 1-({6-[(2-methoxy-4-propylbenzyl)oxy]-1-methyl-3,4-dihydronaphthalen-2-yl}methyl)azetidine-3-carboxylic acid 
• 891859-41-9 6-[(2-methoxy-4-propylbenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde 
• 891859-11-3 (2-methoxy-4-propylphenyl)methanol 
• 119006-58-5 2-hydroxy-4-propylbenzoic acid 

Relevant articles and documents

CATALYTIC FUNNELING OF PHENOLICS

In general, present invention concerns an integrated wood-to-xylochemicals biorefinery, enabling production of renewable phenol, phenolic oligomers, propylene, and carbohydrate pulp from lignocellulosic biomass.

Practical Cleavage of Acetals by Using an Odorless Thiol Immobilized on Silica

A practical, efficient and general method was developed for the deprotection of a variety of aromatic and aliphatic acetals to their corresponding catechol or diol derivatives using thiol immobilized on silica gel. This is an application for the well-known commercial solid-supported thiol (SiliaMetS Thiol). The procedure is mild and amenable to scale-up. It does not require inert atmosphere and clean conversions were observed. This method is applicable to substituted 1,3-benzodioxole and aliphatic acetals with different functionalities. It offers the advantage of a general route with high yield, which can be undertaken at ambient temperature.

Chemo- and Regioselective Hydrogenolysis of Diaryl Ether C-O Bonds by a Robust Heterogeneous Ni/C Catalyst: Applications to the Cleavage of Complex Lignin-Related Fragments

We report the chemo- and regioselective hydrogenolysis of the C-O bonds in di-ortho-substituted diaryl ethers under the catalysis of a supported nickel catalyst. The catalyst comprises heterogeneous nickel particles supported on activated carbon and furnishes arenes and phenols in high yields without hydrogenation. The high thermal stability of the embedded metal particles allows C-O bond cleavage to occur in highly substituted diaryl ether units akin to those in lignin. Preliminary mechanistic experiments show that this catalyst undergoes sintering less readily than previously reported catalyst particles that form from a solution of [Ni(cod)2].