63279-13-0 Usage
Description
(4R)-13-[[2-O-(β-D-Glucopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy]kaur-16-en-18-oic acid 2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl ester is a complex organic compound with a molecular structure that features multiple glucose units attached to a kaurane skeleton. This molecule is characterized by its unique arrangement of glycosidic linkages and hydroxyl groups, which may contribute to its potential biological activities and applications.
Uses
Used in Pharmaceutical Applications:
(4R)-13-[[2-O-(β-D-Glucopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy]kaur-16-en-18-oic acid 2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl ester is used as a potential therapeutic agent for various diseases due to its complex glycosidic structure and potential interactions with biological targets.
Used in Drug Delivery Systems:
In the field of drug delivery, this compound may be utilized as a component of novel drug delivery systems, taking advantage of its unique structural features to improve the bioavailability and targeting of therapeutic agents.
Used in Analytical Chemistry:
(4R)-13-[[2-O-(β-D-Glucopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy]kaur-16-en-18-oic acid 2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl ester may serve as an internal standard or reference compound in the analysis of complex mixtures containing similar glycosylated compounds, such as those found in plant extracts or biological samples.
Used in the Food Industry:
As a nutritive sweetener, this compound may be used as a replacement for sugar in the food and beverage industry, particularly in products targeting consumers with diabetes, high blood pressure, or obesity, due to its non-caloric nature and potential sweetness.
Used in the Cosmetics Industry:
(4R)-13-[[2-O-(β-D-Glucopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy]kaur-16-en-18-oic acid 2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl ester's unique structure and properties may also find applications in the cosmetics industry, where it could be used as an active ingredient in skincare or hair care products, potentially offering moisturizing, anti-aging, or other beneficial effects.
Preparation
The rebaudioside D-rich steviol glycoside preparation (~95% rebaudioside D) is produced via an enzymatic conversion process using a strain of Pichia pastoris that has been genetically modified to express UDPglucosyltransferase EUGTll. In the first stage of manufacturing, a steviol glycoside primary extract from the leaves of 5. rebaudiana Bertoni containing 55±5% of rebaudioside A is produced according to the methodology outlined in the Chemical and Technical Assessment (CTA) published by the Food and Agriculture Organization (FAO)/JECFA for steviol glycosides (FAQ, 2016). In the next step, the steviol glycoside primary extract is further purified to a purity of ~95% rebaudioside A through crystallization, also consistent with the CTA methodology. In the third stage, the P. pastoris production strain is subjected to a fermentation step to express the UGT-glucosyltransferase EUGTll, which is used to catalyze the conversion of the high-purity rebaudioside A extracted from 5. rebaudiana Bertoni to rebaudioside D. In the last stage, the rebaudioside D solution is purified and concentrated according to the methodology described in the steviol glycoside CTA, yielding a final product that contains ~95% rebaudioside D.www.fda.gov
Check Digit Verification of cas no
The CAS Registry Mumber 63279-13-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,2,7 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 63279-13:
(7*6)+(6*3)+(5*2)+(4*7)+(3*9)+(2*1)+(1*3)=130
130 % 10 = 0
So 63279-13-0 is a valid CAS Registry Number.
63279-13-0Relevant articles and documents
Diversity-Oriented Synthesis of Steviol Glycosides
Qiao, Zhi,Liu, Hui,Sui, Jing-Jing,Liao, Jin-Xi,Tu, Yuan-Hong,Schmidt, Richard R.,Sun, Jian-Song
, p. 11480 - 11492 (2018/09/25)
With cheap and easily available mixtures of steviol glycosides as starting materials, a practical method for steviol acquisition has been developed, on the basis of which a facile, diversity-oriented, and economic protocol for the synthesis of structurally defined steviol glycosides was established. The novel approach is featured by the highly efficient glycosylation of sterically hindered and acid-sensitive steviol via orchestrated application of Yu glycosylation, Schmidt glycosylation, and PTC glycosylation. Hence, these high-intensity sweeteners and potential lead compounds for drug development are now readily accessible.
HIGH-PURITY STEVIOL GLYCOSIDES
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, (2016/04/09)
Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2, reb M2, and reb I are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.
RECOMBINANT PRODUCTION OF STEVIOL GLYCOSIDES
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Paragraph 0054; 0360; 0361, (2016/08/17)
Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
