637-69-4 Usage
Description
4-Methoxystyrene, also known as para-methoxystyrene, is an aromatic monomer with the chemical formula C9H10O. It is a clear, colorless liquid that is characterized by the presence of a vinyl group and a methoxy group attached to the benzene ring. This unique structure endows 4-Methoxystyrene with specific chemical properties and reactivity, making it suitable for various applications in different industries.
Uses
Used in Chemical Synthesis:
4-Methoxystyrene is used as a monomer in polymerization reactions, contributing to the formation of polymers with specific properties. Its reactivity and compatibility with other monomers allow for the creation of copolymers with tailored characteristics, such as improved thermal stability, mechanical strength, or chemical resistance.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Methoxystyrene is employed in the synthesis of various active pharmaceutical ingredients (APIs) and intermediates. Its unique chemical structure enables the development of novel drug candidates with potential therapeutic applications.
Used in Organic Chemistry:
4-Methoxystyrene is used as a building block in organic chemistry for the synthesis of various organic compounds. Its reactivity with different reagents allows for the formation of a wide range of products, such as dyes, fragrances, and additives.
Used in Ferric Chloride-Catalyzed Addition:
4-Methoxystyrene is used as a reactant in the ferric chloride-catalyzed addition of activated methylenes to styrenes. This reaction is an important synthetic method for the preparation of various organic compounds, including those with potential applications in the pharmaceutical, agrochemical, and materials science industries.
Used in the Preparation of 1,1,2,2-Tetracyano-3-(p-methoxyphenyl)cyclobutane:
4-Methoxystyrene is used to prepare 1,1,2,2-Tetracyano-3-(p-methoxyphenyl)cyclobutane by reacting with ethenetetracarbonitrile. 4-Methoxystyrene has potential applications in the development of novel materials with unique properties, such as conductivity or magnetism.
Synthesis Reference(s)
Chemistry Letters, 13, p. 1897, 1984The Journal of Organic Chemistry, 52, p. 422, 1987 DOI: 10.1021/jo00379a020Tetrahedron Letters, 35, p. 8773, 1994 DOI: 10.1016/S0040-4039(00)78494-2
Check Digit Verification of cas no
The CAS Registry Mumber 637-69-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,3 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 637-69:
(5*6)+(4*3)+(3*7)+(2*6)+(1*9)=84
84 % 10 = 4
So 637-69-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O/c1-3-8-4-6-9(10-2)7-5-8/h3-7H,1H2,2H3
637-69-4Relevant articles and documents
Hernandez,Chuchani
, p. 923,924, 926-927 (1978)
Functionalized styrene synthesis via palladium-catalyzed C[sbnd]C cleavage of aryl ketones
Dai, Hui-Xiong,Wang, Xing,Wang, Zhen-Yu,Xu, Hui,Zhang, Xu
supporting information, (2022/03/31)
We report herein the synthesis of functionalized styrenes via palladium-catalyzed Suzuki–Miyaura cross-coupling reaction between aryl ketone derivatives and potassium vinyltrifluoroborate. The employment of pyridine-oxazoline ligand was the key to the cleavage of unstrained C[sbnd]C bond. A variety of functional groups and biologically important moleculars were well tolerated. The orthogonal Suzuki–Miyaura coupling demonstrated the synthetic practicability.
Polymerization of Allenes by Using an Iron(II) β-Diketiminate Pre-Catalyst to Generate High Mn Polymers
Durand, Derek J.,Webster, Ruth L.,Woof, Callum R.
supporting information, p. 12335 - 12340 (2021/07/19)
Herein, we report an iron(II)-catalyzed polymerization of arylallenes. This reaction proceeds rapidly at room temperature in the presence of a hydride co-catalyst to generate polymers of weight up to Mn=189 000 Da. We have determined the polymer structure and chain length for a range of monomers through a combination of NMR, differential scanning calorimetry (DSC) and gel permeation chromatography (GPC) analysis. Mechanistically, we postulate that the co-catalyst does not react to form an iron(II) hydride in situ, but instead the chain growth is proceeding via a reactive Fe(III) species. We have also performed kinetic and isotopic experiments to further our understanding. The formation of a highly unusual 1,3-substituted cyclobutane side-product is also investigated.