642086-01-9Relevant articles and documents
Mechanism of the Glutathione Transferase-Catalyzed Conversion of Antitumor 2-Crotonyloxymethyl-2-cycloalkenones to GSH Adducts
Hamilton, Diana S.,Zhang, Xiyun,Ding, Zhebo,Hubatsch, Ina,Mannervik, Bengt,Houk,Ganem, Bruce,Creighton, Donald J.
, p. 15049 - 15058 (2003)
Human glutathione (GSH) transferase (hGSTP1-1) processes with similar kinetic efficiencies the antitumor agents 2-crotonyloxymethyl-2-cyclohexenone (COMC-6), 2-crotonyloxymethyl-2-cycloheptenone (COMC-7), and 2-crotonyloxymethyl-2-cyclopentenone (COMC-5)