70097-13-1

Basic information

• Product Name: 2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID
• Synonyms: CHEMBRDG-BB 6144076;AKOS AUF0715;2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID;2-(4-nitrophenyl)quinoline-4-carboxylic acid(SALTDATA: FREE);2-(4-nitrophenyl)-4-Quinolinecarboxylic acid
• CAS NO: 70097-13-1
• Molecular Formula: C₁₆H₁₀N₂O₄
• Molecular Weight: 294.26
• Mol File: 70097-13-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 527.8°C at 760 mmHg
• Flash Point: 273°C
• Appearance: /
• Density: 1.425g/cm³
• Vapor Pressure: 5.75E-12mmHg at 25°C
• Refractive Index: 1.705
• CAS DataBase Reference: 2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID(70097-13-1)
• EPA Substance Registry System: 2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID(70097-13-1)

Safety Data

• Hazardous Substances Data: 70097-13-1(Hazardous Substances Data)

Usage

General Description

2-(4-Nitro-phenyl)-quinoline-4-carboxylic acid is a chemical compound with the molecular formula C17H10N2O4. It is commonly used as a building block in the synthesis of various pharmaceutical compounds. 2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID has potential medicinal properties and is being studied for its anti-inflammatory and antibacterial activities. It is also used as a fluorescent probe in biochemical and cell biological studies. Its structure consists of a quinoline core with a carboxylic acid moiety and a nitro-substituted phenyl group, which gives the compound its distinctive properties and potential applications in various fields.

InChI:InChI=1/C16H10N2O4/c19-16(20)13-9-15(17-14-4-2-1-3-12(13)14)10-5-7-11(8-6-10)18(21)22/h1-9H,(H,19,20)

Upstream product

• 91-56-5 indole-2,3-dione 
• 100-19-6 (4-nitrophenyl)ethanone 
• 5467-57-2 2-chloroquinoline-4-carboxylic acid 
• 132-60-5 cinchophen 
• 95201-24-4 ethyl 2-(4'-nitrophenyl)-quinoline-4-carboxylate 
• 127-17-3 2-oxo-propionic acid 
• 785-80-8 p-nitrobenzylideneaniline 
• 56680-34-3 3-(4'-nitrobenzoyl)-methyleneindol-2-one 
• 70097-11-9 3-hydroxy-3-(2-oxo-2-(4-nitrophenyl)ethyl)indolin-2-one 
• 555-16-8 4-nitrobenzaldehdye 
• 62-53-3 aniline 

Downstream Products

• 132-60-5 cinchophen 

Relevant articles and documents

Energy efficient Pfitzinger reaction: A novel strategy using a surfactant catalyst

A novel energy efficient method for the Pfitzinger reaction is demonstrated, which is catalysed using a surfactant, cetyltrimethylammonium hydroxide. The surfactant nature of the catalyst caused the substrate to be soluble in aqueous media, which enhanced the interaction of the catalyst with the substrate. An increase in the rate of reaction and more than 78% of energy saving were observed under ultrasonic irradiation.

One-pot synthesis of quinoline-4-carboxylic acid derivatives in water: Ytterbium perfluorooctanoate catalyzed Doebner reaction

Ytterbium perfluorooctanoate [Yb(PFO)3] has been proved to be an efficient catalyst for Doebner reaction of pyruvic acid, aldehydes and amines under mild conditions in water to afford quinoline-4-caboxylic acid derivatives with three component one-pot method in good yields. The process is operationally simple and environmentally benign and the catalyst has readily been recycled for several times with consistent activity. Furthermore, a plausible mechanism for this transformation is also presented.

SYNTHESIS AND ANTIVIRAL ACTIVITY OF 2-QUINOLINE-4-CARBOXYLIC ACIDS

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