70854-63-6Relevant articles and documents
Synthetic studies on coenzyme Q10: Part 2 - A efficient and improved synthesis of coenzyme Q10 via the C5 + C 45 approach
Dai, Hui-Fang,Chen, Fen-Er,Yu, Xiong-Jie
, p. 1317 - 1321 (2007/10/03)
An improved route to coenzyme Q10 (1) starting from commercially available coenzyme Q1 is described. The key steps in this synthesis are the SeO2-mediated oxidation of the protected isoprenylhydroquinone 3 into the (E)-allyl alcohol 5 without the formation of undesired stereoisomer and the one-pot reductive elimination of the phenylsulfonyl and dibenzyl groups in 7 by using naphthalenyllithium.