75204-49-8

Basic information

• Product Name: ethyl 4,5-dioxo-3-phenyl-4,5-dihydronaphtho[1,2-b]furan-2-carboxylate
• Synonyms: ethyl 4,5-dioxo-3-phenyl-4,5-dihydronaphtho[1,2-b]furan-2-carboxylate
• CAS NO: 75204-49-8
• Molecular Weight: 346.339
• Mol File: 75204-49-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4,5-dioxo-3-phenyl-4,5-dihydronaphtho[1,2-b]furan-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4,5-dioxo-3-phenyl-4,5-dihydronaphtho[1,2-b]furan-2-carboxylate(75204-49-8)
• EPA Substance Registry System: ethyl 4,5-dioxo-3-phenyl-4,5-dihydronaphtho[1,2-b]furan-2-carboxylate(75204-49-8)

Safety Data

• Hazardous Substances Data: 75204-49-8(Hazardous Substances Data)

Upstream product

• 83-72-7 2-hydroxynaphtho-1,4-quinone 
• 2216-94-6 phenylpropynoic acid ethyl ester 

Downstream Products

• 75204-51-2 2-phenylnaphtho[1,2-b]furan-4,5-dione 
• 75204-50-1 2-phenyl-3-carbethoxy-4,5-dioxonaphthofuran 
• 62452-63-5 2-phenylnaphtho[2,3-b]furan-4,9-dione 
• 59382-19-3 2-hydroxy-3-(2-phenyl-2-oxo)ethyl-1,4-naphthoquinone 

Relevant articles and documents

Palladium-catalyzed enol/enolate directed oxidative annulation: Functionalized naphthofuroquinone synthesis and bioactivity evaluation

A palladium-promoted oxidative annulation reaction for the synthesis of structurally diverse naphthoquinone-containing heterocycles has been developed, providing switchable access to 1,2-naphthofuroquinones and densely functionalized cyclobutene-fused 1,4-naphthofuroquinones by selective enol/enolate-directed processes. The synthetic application was extended by late-stage functionalization of an anti-HIV drug. The practical value of 1,2-naphthofuroquinone synthesis was highlighted in endothelial protective lead compound development.