75465-37-1 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
2. Heterocyclic organic compound
Explanation
It is a type of organic compound that contains a ring structure with atoms of different elements, in this case, carbon, nitrogen, oxygen, and sulfur.
3. Contains a thiadiazole ring
Explanation
The thiadiazole ring is a five-membered ring with two nitrogen atoms and one sulfur atom, which is a key structural feature of this compound.
4. Contains a phenyl group
Explanation
The phenyl group is a six-carbon aromatic ring with alternating single and double bonds, which is attached to the thiadiazole ring.
5. Used in medicinal chemistry
Explanation
The compound is utilized as a building block for the synthesis of various pharmaceutical drugs due to its versatile chemical properties.
6. Potential as an anti-inflammatory agent
Explanation
Studies have shown that 1,2,4-Thiadiazol-5(2H)-one, 3-phenylmay have the ability to reduce inflammation, which could be useful in treating conditions characterized by inflammation.
7. Potential as an anti-cancer agent
Explanation
The compound has been investigated for its ability to inhibit the growth of cancer cells, making it a potential candidate for cancer treatment.
8. Potential as an antifungal agent
Explanation
Research has indicated that 1,2,4-Thiadiazol-5(2H)-one, 3-phenylmay have the ability to inhibit the growth of fungi, which could be useful in treating fungal infections.
9. Investigated for treatment of neurodegenerative diseases
Explanation
The compound has been studied for its potential to protect against or slow down the progression of neurodegenerative diseases, such as Alzheimer's or Parkinson's disease.
10. Promising pharmacological properties
Explanation
Due to its various potential applications in medicine, 1,2,4-Thiadiazol-5(2H)-one, 3-phenylis considered an important and versatile compound with promising pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 75465-37-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,4,6 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 75465-37:
(7*7)+(6*5)+(5*4)+(4*6)+(3*5)+(2*3)+(1*7)=151
151 % 10 = 1
So 75465-37-1 is a valid CAS Registry Number.
75465-37-1Relevant articles and documents
A continuous flow synthesis and derivatization of 1,2,4-thiadiazoles
Baumann, Marcus,Baxendale, Ian R.
, p. 6218 - 6223 (2017/09/30)
A continuous flow process is presented that enables the efficient synthesis and derivatization of 1,2,4-thiadiazole heterocycles. Special attention was given to the safe handling of the versatile yet hazardous trichloromethane sulfenylchloride reagent including its in-line quenching in order to eliminate malodourous and corrosive by-products. Based on this flow method gram quantities of 5-chloro-3-phenyl-1,2,4-thiadiazole were safely prepared allowing for further elaboration of this valuable building block by reaction with different nitrogen-, sulfur- and oxygen-based nucleophiles. This synthetic approach was subsequently applied to generate a series of bromophenyl-5-chloro-1,2,4-thiadiazoles providing a valuable entry towards further structural diversification on this important heterocyclic scaffold.
REACTION OF BENZAMIDE OXIME DERIVATIVES WITH CHLOROCARBONYLSULFENYL CHLORIDE
Kawashima, Etsuko,Ando, Yuko,Takada, Toyozo,Tabei, Katsumi
, p. 181 - 190 (2007/10/02)
Benzamide oxime derivatives (1) were reacted with chlorocarbonylsulfenyl chloride (2) in the presence of a base as a catalyst to afford 3-aryl-4,5-dihydro-1,2,4-thiadiazol-5-one (3), 3-aryl-4,5-dihydro-1,2,4-oxadiazol-5-one (4) and di(benzamide) O,O'-carboxime (5) derivatives in moderate yields.The reaction of N-ethyl-p-toluamide oxime (7) with 2 gave 4-ethyl-4,5-dihydro-3-(p-tolyl)-1,2,4-thiadiazol-5-one (8) and 4-ethyl-4,5-dihydro-3-(p-tolyl)-1,2,4-oxadiazol-5-one (9).
