78443-35-3

Basic information

• Product Name: 3-[1,1'-biphenyl]-4-yl-3-oxopropanenitrile
• Synonyms: 3-[1,1'-biphenyl]-4-yl-3-oxopropanenitrile
• CAS NO: 78443-35-3
• Molecular Formula: C₁₅H₁₁NO
• Molecular Weight: 221.26
• Mol File: 78443-35-3.mol
• Article Data: 15

Chemical Properties

• Melting Point: 116-118°
• Boiling Point: 418.129 °C at 760 mmHg
• Flash Point: 206.677 °C
• Appearance: /
• Density: 1.128 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 3-[1,1'-biphenyl]-4-yl-3-oxopropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[1,1'-biphenyl]-4-yl-3-oxopropanenitrile(78443-35-3)
• EPA Substance Registry System: 3-[1,1'-biphenyl]-4-yl-3-oxopropanenitrile(78443-35-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 78443-35-3(Hazardous Substances Data)

Usage

General Description

3-[1,1'-biphenyl]-4-yl-3-oxopropanenitrile is a chemical compound that belongs to the family of biphenyl compounds. It is a nitrile derivative, characterized by a nitrile group attached to a 3-oxopropane moiety. 3-[1,1'-biphenyl]-4-yl-3-oxopropanenitrile has potential applications in the fields of organic synthesis and medicinal chemistry, due to its unique structure and reactivity. Its ability to undergo various chemical reactions makes it a versatile building block for the synthesis of more complex organic molecules. Additionally, its biphenyl core imparts unique properties that can be exploited for the development of novel materials and pharmaceuticals. However, the compound's specific uses and properties would depend on its chemical and physical characteristics, as well as its interactions with other substances.

InChI:InChI=1/C15H11NO/c16-11-10-15(17)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10H2

Upstream product

• 101335-77-7 N-methoxy-N-methyl-[1,1'-biphenyl]-4-carboxamide 
• 75-05-8 acetonitrile 
• 60131-48-8 (E)-3-Biphenyl-4-yl-3-chloro-acrylonitrile 
• 5122-94-1 4-biphenylboronic acid 
• 109-77-3 malononitrile 
• 773837-37-9 sodium cyanide 
• 135-73-9 2-Bromo-4'-phenylacetophenone 
• 720-75-2 methyl 4-phenylbenzoate 
• 6301-56-0 ethyl 4-phenylbenzoate 
• 1116-98-9 cyanoacetic acid tert-butyl ester 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 82102-37-2 9-methyl-9H-fluorene-9-carbonyl chloride 
• 13138-21-1 diazoacetonitrile 
• 3218-36-8 4-Phenylbenzaldehyde 

Downstream Products

• 90284-20-1 (Z)-2-(Biphenyl-4-carbonyl)-3-(4-fluoro-phenyl)-acrylonitrile 
• 88876-75-9 (Z)-2-(Biphenyl-4-carbonyl)-3-(4-chloro-phenyl)-acrylonitrile 
• 88876-74-8 (Z)-2-(Biphenyl-4-carbonyl)-3-(4-methoxy-phenyl)-acrylonitrile 
• 1401051-14-6 2,3,5,7,8-pentaphenylnaphtho[1,8-bc]pyran-9-carbonitrile 
• 84864-05-1 3-(Biphenyl-4-carbonyl)-4-hydroxy-pyrrole-2,5-dione 
• 223423-52-7 2-amino-3-(4-phenylbenzoyl)-4,5,6,7-tetrahydrothieno(2,3-c)pyridine 
• 223423-49-2 2-amino-3-(4-phenylbenzoyl)-6-(benzyloxycarbonyl)-4,5,6,7-tetrahydrothieno(2,3-c)pyridine 
• 90284-18-7 (Z)-2-(Biphenyl-4-carbonyl)-3-(4-isopropyl-phenyl)-acrylonitrile 

Relevant articles and documents

Selective Synthesis of β-Ketonitriles via Catalytic Carbopalladation of Dinitriles

A practical, convenient, and highly selective method of synthesizing β-ketonitriles from the Pd-catalyzed addition of organoboron reagents to dinitriles has been developed. This method provides excellent functional-group tolerance, a broad scope of substrates, and the convenience of using commercially available substrates. The method is expected to show further utility in future synthetic procedures.

One-pot synthesis of dual-state emission (DSE) luminogens containing the V-shape furo[2,3-b]furan scaffold

To discover novel fluorophores of solution and solid dual-state emission (DSE) materials, unique V-shape furo[2,3-b]furans have been designed and synthesized by a one-pot method for the first time and their photoluminescent properties have been explored in benzene, THF, DMF and DMSO, as well as in the solid state. As the best example, 2,5-bis(4-(9H-carbazol-9-yl)phenyl)-6a-amino-3a,6a-dihydrofuro[2,3-b]furan-3,3a,4-tricarbonitrile (3g) exhibited solution and solid DSE properties in THF, benzene, and in the solid state with quantum yields of 55%, 92%, and 45%, respectively.

Deadly KCN and pricey metal free track for accessing β-ketonitriles employing mild reaction conditions

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