80715-20-4

Basic information

• Product Name: 1,3-Dioxol-2-one, 4-(bromomethyl)-5-phenyl-
• CAS NO: 80715-20-4
• Molecular Formula: C10H7BrO3
• Molecular Weight: 255.068
• Mol File: 80715-20-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxol-2-one, 4-(bromomethyl)-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxol-2-one, 4-(bromomethyl)-5-phenyl-(80715-20-4)
• EPA Substance Registry System: 1,3-Dioxol-2-one, 4-(bromomethyl)-5-phenyl-(80715-20-4)

Safety Data

• Hazardous Substances Data: 80715-20-4(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic compound

Structure

Contains a dioxolone ring and a phenyl group

Bromomethyl group attachment

Position 4 of the dioxolone ring

Primary use

Organic synthesis as a building block for complex molecules

Utility

Useful precursor in the synthesis of biologically active compounds and pharmaceutical products

Phenyl group property

Confers aromatic and hydrophobic properties to the molecule

Application

Exploited in drug design and related applications

Upstream product

• 93-54-9 1-Phenyl-1-propanol 
• 93-55-0 1-phenyl-propan-1-one 
• 5650-40-8 2-hydroxypropiophenone 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 40352-53-2 4-phenyl-5-methyl-1,3-dioxol-4-en-2-one 

Downstream Products

• 108331-00-6 mecillinam (2-oxo-5-phenyl-1,3-dioxol-4-yl)methyl ester hydrochloride 
• 173604-88-1 (5-phenyl-2-oxo-1,3-dioxol-4-en-4-yl)methyl p-nitrophenyl carbonate 
• 173604-85-8 4-(hydroxymethyl)-5-phenyl-1,3-dioxol-4-en-2-one 
• 85871-32-5 1,1-dioxopenicillanic acid (5-phenyl-2-oxo-1,3-dioxolen-4-yl)-methyl ester 
• 80715-21-5 ampicillin (2-oxo-5-phenyl-1,3-dioxolen-4-yl)methyl ester hydrochloride 
• 137713-29-2 5-Phenyl-4-phenylthiomethyl-1,3-dioxol-2-one 
• 93034-36-7 4-iodomethyl-2-oxo-5-phenyl-1,3-dioxolene 
• 172688-07-2 (2-oxo-5-phenyl-1,3-dioxol-4-yl)methylformate 
• 137713-30-5 4-(4-Nitrophenylthio)methyl-5-phenyl-1,3-dioxol-2-one 

Relevant articles and documents

Influenza virus replication inhibitors and uses thereof (by machine translation)

The invention provides a compound as an influenza virus replication inhibitor, a method for preparing the same, a pharmaceutical composition containing the compound and application. (by machine translation)

PRODRUGS OF IMIDAZOLE CARBOXYLIC ACIDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS

Prodrugs of imidazole carboxylic acids which are AII antagonists useful in treating hypertension, pharmaceutical compositions thereof and a method of treating hypertension using such prodrugs are disclosed.

Ester of 1,1-dioxopenicillanic acid, and use thereof as β-lactamase inhibitor

A 1,1-dioxopenicillanic acid ester represented by formula (I) STR1 wherein R represents a methyl or phenyl group. The ester of formula (I) may be prepared by reacting 1,1-dioxopenicillanic acid or its salt with a compound represented by formula (III) STR2 wherein R is as defined above, and X represents a halogen atom, or by oxidizing a compound of formula (V) STR3 wherein R is as defined above. The ester of the formula (I) is useful as a β-lactamase inhibitor and may be used in association with a β-lactam antibiotic.