83712-60-1

Basic information

• Product Name: defibrotide
• Synonyms: defibrotide;Dasovas;Defibrinotide;Fraction p;Noravid;Prociclide
• CAS NO: 83712-60-1
• Molecular Weight: 0
• Mol File: 83712-60-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: defibrotide(CAS DataBase Reference)
• NIST Chemistry Reference: defibrotide(83712-60-1)
• EPA Substance Registry System: defibrotide(83712-60-1)

Safety Data

• Hazardous Substances Data: 83712-60-1(Hazardous Substances Data)

Usage

Description

Defibrotide is an antithrombotic, partially-depolymerized polydeoxyribonucleotide derived from bovine lungs. It is known for its potential in treating various conditions, including myocardial and severe lower limb ischemia, renal failure due to thrombotic microangiopathy, thrombophlebitis, and as a prophylactic for deep vein thrombosis, possibly through the stimulation of PCI2.

Uses

Used in Cardiovascular Applications:
Defibrotide is used as an antithrombotic agent for the treatment of myocardial and severe lower limb ischemia. It helps improve blood flow and reduce the risk of blood clot formation in these areas.
Used in Renal Applications:
Defibrotide is used as a therapeutic agent for renal failure due to thrombotic microangiopathy. It aids in mitigating the damage caused by the condition and supports the recovery of kidney function.
Used in Vascular Applications:
Defibrotide is used as a treatment for thrombophlebitis, an inflammation of a vein usually caused by a blood clot. It helps in reducing inflammation and preventing further clot formation.
Used in Prophylactic Applications:
Defibrotide is used as a prophylactic agent for the prevention of deep vein thrombosis. It helps in maintaining proper blood flow and reducing the risk of clot formation in the deep veins.
Brand names: Noravid and Prociclide.

Originator

Crinos (Italy)