84985-78-4 Usage
Description
(3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol is a derivative of Vitamin D, characterized as an off-white solid. It is a complex steroidal structure with specific stereochemistry at various positions, which contributes to its potential applications in pharmaceutical chemistry.
Uses
Used in Pharmaceutical Industry:
(3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol is used as an intermediate for the preparation of Vitamin-based antibiotics. Its unique structure allows it to serve as a key component in the synthesis of antibiotics that can potentially target specific pathogens or exhibit enhanced antimicrobial properties.
As a derivative of Vitamin D, this compound may also find applications in other areas of pharmaceutical development, such as in the creation of drugs targeting specific diseases or conditions where Vitamin D plays a crucial role in treatment or management. Its chemical properties and structural features make it a promising candidate for further research and development in the pharmaceutical field.
Check Digit Verification of cas no
The CAS Registry Mumber 84985-78-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,9,8 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 84985-78:
(7*8)+(6*4)+(5*9)+(4*8)+(3*5)+(2*7)+(1*8)=194
194 % 10 = 4
So 84985-78-4 is a valid CAS Registry Number.
InChI:InChI=1/C28H46O3/c1-18(2)19(3)8-9-21(5)24-12-13-25-27(24,6)14-7-15-28(25,31)26(30)17-22-16-23(29)11-10-20(22)4/h8-9,17-19,21,23-26,29-31H,4,7,10-16H2,1-3,5-6H3/b9-8+,22-17-/t19?,21-,23-,24-,25?,26?,27-,28?/m1/s1
84985-78-4Relevant articles and documents
Synthesis of (17R)-17-methylincisterol, a highly degraded marine steroid
De Riccardis, Francesco,Spinella, Aldo,Izzo, Irene,Giordano, Assunta,Sodano, Guido
, p. 4303 - 4306 (1995)
The synthesis of (17R)-17-methylincisterol, a highly degraded marine steroid, has been achieved starting from vitamin D2 in 8 steps and in 13% overall yield. Its O-demethyl analog, which is an intermediate in the synthetic sequence, is possibly
Vitamin D modified based on amino acid2 Derivatives, synthesis and application
-
Paragraph 0041-0043, (2017/08/19)
The invention discloses an amino acid modification based vitamin D2 derivative, synthesis and applications. Vitamin D2 fragment alcohol is prepared with the vitamin D2 serving as raw materials through redox reaction, and the amino acid modification based
Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway
Deberardinis, Albert M.,Banerjee, Upasana,Miller, Michele,Lemieux, Steven,Hadden
scheme or table, p. 4859 - 4863 (2012/08/13)
A structure-activity relationship study to elucidate the structural basis for hedgehog (Hh) signaling inhibition by vitamin D3 (VD3) was performed. Functional and non-functional regions of VD3 and VD2 were obtained through straightforward synthetic means