86299-47-0 Usage
Description
(Z)-2-Amino-alpha-[1-(tert-butoxycarbonyl)]-1-methylethoxyimino-4-thiazolacetic acid is a complex organic compound characterized by its unique molecular structure, featuring a thiazolacetic acid core with various functional groups attached. (Z)-2-Amino-alpha-[1-(tert-butoxycarbonyl)]-1-methylethoxyimino-4-thiazolacetic acid is known for its role as a key intermediate in the synthesis of pharmaceuticals, particularly in the production of antibiotics.
Used in Pharmaceutical Industry:
(Z)-2-Amino-alpha-[1-(tert-butoxycarbonyl)]-1-methylethoxyimino-4-thiazolacetic acid is used as a synthetic intermediate for the production of Ceftazidime (C244100), a third-generation cephalosporin antibiotic. Ceftazidime is effective against a broad range of Gram-negative bacteria, including Pseudomonas aeruginosa, and is used to treat various severe infections such as pneumonia, skin infections, and bone infections. The role of this intermediate in the synthesis process is crucial for the development of this life-saving antibiotic.
Check Digit Verification of cas no
The CAS Registry Mumber 86299-47-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,2,9 and 9 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 86299-47:
(7*8)+(6*6)+(5*2)+(4*9)+(3*9)+(2*4)+(1*7)=180
180 % 10 = 0
So 86299-47-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H19N3O5S/c1-12(2,3)20-10(19)13(4,5)21-16-8(9(17)18)7-6-22-11(14)15-7/h6H,1-5H3,(H2,14,15)(H,17,18)/p-1/b16-8+
86299-47-0Relevant articles and documents
Process for the preparation of crystalline (Z)-2-(2-tert.-butoxycarbonylprop-2-oxyimino)-2-(2-triphenylmethylaminothiazol-4-yl) acetic acid in association with N,N-dimethylformamide
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, (2008/06/13)
The present invention relates to the preparation of crystalline (Z)-2-(2-tert.-butoxycarbonyl prop-2-oxyimino)-2-(2-triphenylmethylaminothiazol-4-yl) acetic acid of the following formula which is useful in the synthesis of β-lactam antibiotics such is ceftazidime.
