88901-36-4

Basic information

• Product Name: Mogroside V
• Synonyms: Momordica grosvenori swingle;(24R)-3β-[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-24-[2-O,6-O-bis(β-D-glucopyranosyl)-β-D-glucopyranosyloxy]cucurbit-5-ene-11α,25-diol;beta-D-Glucopyranoside, (3beta,9beta,10alpha,11alpha,24R)-3-((6-o-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl o-beta-D-glucopyranosyl-(1-2)-o-(beta-D-glucopyranosyl-(1-6))-;Mogrol-3-o-(beta-D-glucopyranosyl (1-6)-beta-D-glucopyranoside)-24-o-((beta-D-glucopyranosyl (1-2))-(beta-D-glucopyranosyl(1-6))-beta-D-glucopyranoside);MomordicagrosvenoriSwingleP.E;MOGROSIDE V(P);Mogroside V ,98%;Momordica grosvenori
• CAS NO: 88901-36-4
• Molecular Formula: C₆₀H₁₀₂O₂₉
• Molecular Weight: 1287.44
• EINECS: 695-005-3
• Product Categories: Food Additives;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Miscellaneous Natural Products;Inhibitors
• Mol File: 88901-36-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 197～201℃
• Appearance: yellow powder
• Density: 1.51
• Refractive Index: 1.643
• Storage Temp.: 2-8°C
• Solubility: Methanol (Slightly, Sonicated), Pyrindine (Slightly), Water (Slightly)
• PKA: 12.82±0.70(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: Mogroside V(CAS DataBase Reference)
• NIST Chemistry Reference: Mogroside V(88901-36-4)
• EPA Substance Registry System: Mogroside V(88901-36-4)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 88901-36-4(Hazardous Substances Data)

Usage

Description

Mogroside V is a triterpenoidal saponin found in the fruit of Siraitia grosvenorii Swingle, known for its natural sweetness and potential anti-inflammatory properties. As a white powder, it is recognized for its unique chemical properties that make it a valuable addition to various industries.

Uses

Used in Food Industry:
Mogroside V is used as a natural sweetener for its ability to provide sweetness without the high caloric content of sugar. This makes it an ideal substitute for sugar in various food products, catering to health-conscious consumers and those with diabetes.
Used in Pharmaceutical Industry:
Mogroside V is used as a potential anti-inflammatory agent, particularly for lung airway conditions. Its ability to reduce inflammation can contribute to improved respiratory health and provide relief for individuals suffering from respiratory issues.
Used in Cosmetics Industry:
Given its anti-inflammatory properties, Mogroside V can also be utilized in the cosmetics industry for skincare products. It may help soothe and reduce inflammation in the skin, promoting a healthier and more radiant complexion.

InChI:InChI=1/C60H102O29/c1-23(9-13-35(57(4,5)79)88-55-50(89-54-49(78)43(72)38(67)29(20-63)84-54)45(74)40(69)31(86-55)22-81-52-47(76)42(71)37(66)28(19-62)83-52)24-15-16-58(6)32-12-10-25-26(60(32,8)33(64)17-59(24,58)7)11-14-34(56(25,2)3)87-53-48(77)44(73)39(68)30(85-53)21-80-51-46(75)41(70)36(65)27(18-61)82-51/h10,23-24,26-55,61-79H,9,11-22H2,1-8H3/t23-,24-,26-,27-,28-,29+,30?,31-,32+,33-,34+,35?,36-,37-,38+,39-,40-,41+,42+,43-,44+,45+,46-,47-,48-,49+,50-,51-,52-,53+,54-,55+,58+,59-,60+/m1/s1

Synthetic route

11-oxo-mogroside V → 11-epi-mogroside V + 3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl (24R)-cucurbit-5-ene-3β,11α,24,25-tetrol 24-O-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranoside-(1->6)]-β-D-glucopyranoside (88901-36-4)

Conditions	Yield
With sodium tetrahydroborate In 1,4-dioxane at 50℃; for 72h;

3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl (24R)-cucurbit-5-ene-3β,11α,24,25-tetrol 24-O-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranoside-(1->6)]-β-D-glucopyranoside (88901-36-4) → 3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl (24R)-cucurbit-5-en-11-one-3β,24,25-triol 24-O-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranoside-(1->6)]-β-D-glucopyranoside

Conditions	Yield
With potassium permanganate In water for 1.5h; Reagent/catalyst;	96.71%

3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl (24R)-cucurbit-5-ene-3β,11α,24,25-tetrol 24-O-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranoside-(1->6)]-β-D-glucopyranoside (88901-36-4) → D-glucose (50-99-7)

Conditions	Yield
With hydrogenchloride; water for 1.5h;

Downstream Products

• 50-99-7 D-glucose 

Relevant articles and documents

COMPOSITIONS

A sweetness modifying composition comprising at least one high-intensity sweetener chosen from steviol glycosides and/or mogrosides and at least one low-potency sweetener chosen from cellobiose, psicose, cyclamate and/or 11-O-mogroside V, and a sweetened composition comprising said sweetness modifying composition and at least one other sweetener; the uses of said sweetened compositions and sweetness modifying compositions; methods of making said sweetened compositions and sweetness modifying compositions.