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Name	(2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol	EINECS	N/A
CAS No.	5605-46-9	Density	1.364
PSA	86.22000	LogP	1.12990
Solubility	N/A	Melting Point	132-133 ℃
Formula	C₁₂H₁₇NO₄S	Boiling Point	N/A
Molecular Weight	271.337	Flash Point	N/A
Transport Information	N/A	Appearance	N/A
Safety		Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	N-Tosylhydroxy-L-prolinol;	Article Data	10

(2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol Specification

The (3R,5S)-5-(Hydroxymethyl)-1-tosylpyrrolidin-3-ol, with the CAS registry number 5605-46-9, is also known as N-Tosylhydroxy-L-prolinol. This chemical's molecular formula is C₁₂H₁₇NO₄S and molecular weight is 271.33.

Preparation: this chemical can be prepared by trans-4-hydroxy-1-(toluene-4-sulfonyl)-L-proline by heating. This reaction will need reagent BH₃ and solvent tetrahydrofuran with the reaction time of 10 hours. The yield is about 88%.

(3R,5S)-5-(Hydroxymethyl)-1-tosylpyrrolidin-3-ol can be prepared by trans-4-hydroxy-1-(toluene-4-sulfonyl)-L-proline by heating

Uses of (3R,5S)-5-(Hydroxymethyl)-1-tosylpyrrolidin-3-ol: it can be used to produce toluene-4-sulfonic acid 4-hydroxy-1-(toluene-4-sulfonyl)-pyrrolidin-2-ylmethyl ester at the temperature of -20 °C. It will need reagent pyridine with the reaction time of 2 hours. The yield is about 90%.

(3R,5S)-5-(Hydroxymethyl)-1-tosylpyrrolidin-3-ol can be used to produce toluene-4-sulfonic acid 4-hydroxy-1-(toluene-4-sulfonyl)-pyrrolidin-2-ylmethyl ester at the temperature of -20 °C

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