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Basic information

  • Name:
  • (S)-(-)-Indoline-2-carboxylic acid

  • CAS No.:
  • 79815-20-6

  • Molecular Structure:
  • Formula:
  • C9H9NO2
  • Molecular Weight:
  • 163.17
  • Synonyms:
  • (S)-(-)-Indoline-2-carboxylic acid 79815-20-6;S-(-)-Indoline-2-carboxylic acid;(S)-(-) Indole-2-Carboxylic Acid;s-(-)- indoline- 2- carboxylic acid;S-Indoline-2-carboxylic acid;(S)-(-)-Indolene-2-Carboxylic Acid;S-(-)Indoline-2-carboxylic acid;(S)-Indoline-2-Carboxylic Acid;(S)-Indoline-2-formic acid;(-)-(S)-2-Indolinecarboxylic acid;(S)-(-)Indoline-2-CarboxylicAcid;(2S)-indoline-2-carboxylic acid;
  • Density:
  • 1.286 g/cm3
  • Melting Point:
  • 177 °C (dec.)(lit.)
  • Boiling Point:
  • 380 °C at 760 mmHg
  • Flash Point:
  • 183.6 °C
  • Appearance:
  • white to light yellow crystal powder
  • Hazard Symbols:
  • HarmfulXn
  • Risk Codes:
  • 43-48/22-62
  • Safety Description:
  • 22-25-26-36/37 Details

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Chemistry

The Molecular Structure of (S)-(-)-Indoline-2-carboxylic acid (CAS NO.79815-20-6):

Empirical Formula: C9H9NO2
Molecular Weight: 163.1733
Appearance: white to light yellow crystal powder
 Nominal Mass: 163 Da
Average Mass: 163.1733 Da
Monoisotopic Mass: 163.063329 Da 
Index of Refraction: 1.598
Molar Refractivity: 43.27 cm3
Molar Volume: 126.8 cm3
Surface Tension: 52.2 dyne/cm
Density: 1.286 g/cm3
Flash Point: 183.6 °C
Enthalpy of Vaporization: 66.26 kJ/mol
Boiling Point: 380 °C at 760 mmHg
Vapour Pressure: 1.88E-06 mmHg at 25°C 
Refractive index: -116 ° (C=1, 2mol/L HCl)
Storage temp: Store at 0°C
Product Categories: PYRROLE;Indoles and derivatives;pharmacetical;chiral;PERINDOPRIL;(intermediate of perindopril);Indoles;Chiral Compound;Asymmetric Synthesis;Chiral Catalysts, Ligands, and Reagents;Proline-Based Organocatalysts

Uses

 (S)-(-)-Indoline-2-carboxylic acid (CAS NO.79815-20-6) is mainly used in the treatment of cardiovascular and cerebrovascular diseases.

Safety Profile

Hazard Codes: HarmfulXn
Risk Statements: 43-48/22-62 
R43: May cause sensitization by skin contact
R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed
R62: Risk of impaired fertility
Safety Statements: 22-25-26-36/37 
S22: Do not breathe dust
S25: Avoid contact with eyes
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37: Wear suitable protective clothing and gloves
WGK Germany: 2

Specification

 (S)-(-)-Indoline-2-carboxylic acid (CAS NO.79815-20-6) is also called as (R)-1h-indole-2-carboxylic acid ; (R)-2,3-dihydro-1h-indole-2-carboxylic acid ; (R)-(+)-2,3-dihydroindole-2-carboxylic acid ; Perindopril intermediate ; (2S)-indoline-2-carboxylic acid ; (2S)-2,3-dihydro-1h-indole-2-carboxylic acid ; (S)-(-)-indoline-2-carboxylicacid98% .

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