The (Z)-Hymenialdisine, with the CAS registry number 82005-12-7, is also known as Pyrrolo(2,3-c)azepin-8(1H)-one,4-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-, (4Z)-. It belongs to the product categories of Protein Kinase Inhibitors and Activators; Heterocycles; Tyrosine Kinase Inhibitors. This chemical's molecular formula is C₁₁H₁₀BrN₅O₂ and molecular weight is 324.13. What's more, it is light yellow solid and it should be kept in a cold and dry place.

Preparation of (Z)-Hymenialdisine: this chemical can be prepared by 4-(2-Amino-3H-imidazol-4-yl)-2,5-dibromo-6,7-dihydro-1H-pyrrolo[2,3-c]azepin-8-one. This reaction needs reagent AcOH at temperature of 120 °C. The reaction time is 48 hours. The yield is 65 %.

Uses of (Z)-Hymenialdisine: (1) it is used as a potent inhibitor of a variety of kinases including MEK-1, GSK-3, and CKI; (2) it also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations; (3) it is used as a marine sponge alkaloid, a natural product.