|CAS No.||103-85-5||Density||1.294 g/cm3|
|Formula||C7H8N2S||Boiling Point||266.7 °C at 760 mmHg|
|Molecular Weight||152.23||Flash Point||115.1 °C|
|Transport Information||UN 2811 6.1/PG 1||Appearance||white crystalline powder|
|Molecular Structure||Hazard Symbols||T+|
Thiourea,phenyl- (9CI);Urea, 1-phenyl-2-thio- (8CI);1-Phenyl-2-thiourea;1-Phenylthiourea;N-Phenylthiourea;NSC 5779;PTU;Phenylthiocarbamide;Phenylthiourea;U 6324;a-Phenylthiourea;
Product Name: 1-Phenyl-2-thiourea (103-85-5)
Molecular Formula: C7H8N2S
Molecular Weight: 152.22g/mol
Mol File: 103-85-5.mol
Appearance: white crystalline powder
Melting Point: 145-150 °C(lit.)
Boiling point: 266.7 °C at 760 mmHg
Storage Temperature: Poison room
Flash Point: 115.1 °C
Density: 1.294 g/cm3
Water Solubility: negligible
Stability: Stable. Incompatible with strong acids, strong oxidizing agents, strong bases.
Product Categories: Benzene derivatives
Synonyms of 1-Phenyl-2-thiourea (103-85-5): 1-phenyl-2-thio-ure ; alpha-Phenylthiourea ; Fenylthiomocovina ; NCI-C02017 ; phenyl-thioure ; phenylthiourea0 ; Rcra waste number P093 ; rcrawastenumberp093 .
1-Phenyl-2-thiourea (103-85-5) is used in the manufacture of rodenticides and in medical genetics.It's for the production of 2 - amino-benzothiazole, 3 - methyl-benzothiazole hydrazone such as dye intermediates. Also it's used as analytical reagent.
From the first with sulfuric acid aniline salt, and then carry out addition reaction of sodium cyanide with sulfur derived.
1-Phenyl-2-thiourea (103-85-5) is classified as extremely toxic. The probable oral lethal dose is 5-50 mg/kg or between 7 drops and 1 teaspoon for a 70 kg (150 lb.) person.
|Organism||Test Type||Route||Reported Dose (Normalized Dose)||Effect||Source|
|mouse||LD50||intraperitoneal||25mg/kg (25mg/kg)||National Technical Information Service. Vol. AD277-689,|
|mouse||LD50||oral||10mg/kg (10mg/kg)||Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973,|
|rabbit||LD50||oral||40mg/kg (40mg/kg)||Journal of Medicinal and Pharmaceutical Chemistry. Vol. 4, Pg. 109, 1961.|
|rat||LD50||intraperitoneal||5mg/kg (5mg/kg)||ENDOCRINE: HYPERGLYCEMIA||Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 186, 1947.|
|rat||LD50||oral||3mg/kg (3mg/kg)||Journal of Medicinal and Pharmaceutical Chemistry. Vol. 4, Pg. 109, 1961.|
NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-148 ,1978. . EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory.
Dangerous disaster hazard; emits toxic fumes of oxides of sulfur and nitrogen when heated to decomposition. Avoid acids or acid fumes.
Safety Information of 1-Phenyl-2-thiourea (103-85-5):
Hazard Codes: T+
Risk Statements: 28-43
28: Very Toxic if swallowed
43: May cause sensitization by skin contact
Safety Statements: 28-36/37-45
28: After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36: Wear suitable protective clothing
37: Wear suitable gloves
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
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