The 10H-Pyrido[3,2-b][1,4]benzothiazine, with the CAS registry number 261-96-1, is also known as 1-Azaphenothiazine. Its EINECS registry number is 205-973-7. This chemical's molecular formula is C₁₁H₈N₂S and molecular weight is 200.25962. What's more, both its IUPAC name and systematic name are the same which is called 10H-Pyrido[3,2-b][1,4]benzothiazine.

Physical properties about this chemical are: (1)ACD/LogP: 2.66; (2)#of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.65; (4)ACD/LogD (pH 7.4): 2.66; (5)ACD/BCF (pH 5.5): 61.25; (6)ACD/BCF (pH 7.4): 61.64; (7)ACD/KOC (pH 5.5): 660.73; (8)ACD/KOC (pH 7.4): 664.98; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 41.43 Å²; (13)Index of Refraction: 1.684; (14)Molar Refractivity: 58.78 cm³; (15)Molar Volume: 154.8 cm³; (16)Polarizability: 23.3×10^-24cm³; (17)Surface Tension: 59.1 dyne/cm; (18)Density: 1.293 g/cm³; (19)Flash Point: 197 °C; (20)Enthalpy of Vaporization: 65.32 kJ/mol; (21)Boiling Point: 402.1 °C at 760 mmHg; (22)Vapour Pressure: 1.13E-06 mmHg at 25 °C.

Preparation of 10H-Pyrido[3,2-b][1,4]benzothiazine: this chemical can be prepared by 2-Methyl-benzothiazole.



This reaction needs reagent I₂ and solvents Diphenyl ether and
Biphenyl at temperature of 200 ~ 205 °C. The reaction time is 2.5 hours. The yield is 45 %.

Uses of 10H-Pyrido[3,2-b][1,4]benzothiazine: it is used to produce other chemicals. For example, it is used to produce 10-Pyridin-2-yl-10H-benzo[b]pyrido[2,3-e][1,4]thiazine.



The reaction occurs with reagents 2-Chloro-pyridine, Potassium iodide, Potassium carbonate, Copper bronze powder. This reaction will occur at temperature of 230 ~ 250 °C for 4 days. The yield is 65 %.

You can still convert the following datas into molecular structure:
(1) SMILES: n2c1Nc3c(Sc1ccc2)cccc3
(2) InChI: InChI=1/C11H8N2S/c1-2-5-9-8(4-1)13-11-10(14-9)6-3-7-12-11/h1-7H,(H,12,13)
(3) InChIKey: UKDZROJJLPDLDO-UHFFFAOYAV