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2-(Ethylamino)ethanol

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Name

2-(Ethylamino)ethanol

EINECS 203-797-5
CAS No. 110-73-6 Density 0.883 g/cm3
PSA 32.26000 LogP -0.02090
Solubility miscible with water Melting Point -6 °C
Formula C4H11NO Boiling Point 169.5 °C at 760 mmHg
Molecular Weight 89.1374 Flash Point 71.1 °C
Transport Information UN 2810 6.1/PG 3 Appearance Clear colorless to slightly yellowish liquid
Safety 26-36/37/39-45-36 Risk Codes 22-24-41-34
Molecular Structure Molecular Structure of 110-73-6 (2-(Ethylamino)ethanol) Hazard Symbols ToxicT
Synonyms

(2-Hydroxyethyl)ethylamine;2-(Monoethylamino)ethanol;2-(N-Ethylamino)ethanol;Amino Alcohol MEM;N-(2-Hydroxyethyl)ethylamine;N-Ethyl-2-aminoethanol;N-Ethyl-N-(2-hydroxyethyl)amine;N-Ethyl-N-(b-hydroxyethyl)amine;N-Ethylethanolamine;N-Ethylmonoethanolamine;

Article Data 35

2-(Ethylamino)ethanol Synthetic route

75-21-8

oxirane

75-04-7

ethylamine

110-73-6

2-(Ethylamino)ethanol

Conditions
ConditionsYield
In water at 35℃; for 0.0444444h; Temperature;94%
In ethanol; water at 30 - 40℃;45%
100-37-8

2-(Diethylamino)ethanol

A

50-00-0

formaldehyd

B

75-04-7

ethylamine

C

75-07-0

acetaldehyde

D

109-89-7

diethylamine

E

110-73-6

2-(Ethylamino)ethanol

Conditions
ConditionsYield
With water at 25℃; Product distribution; Mechanism; anodic oxidation, carbonate buffer, pH 10; effect of substituents investigated with different types of β-alkanolamines;A 5%
B 1.6%
C 72%
D 20%
E 73%
100-37-8

2-(Diethylamino)ethanol

A

50-00-0

formaldehyd

B

75-07-0

acetaldehyde

C

109-89-7

diethylamine

D

110-73-6

2-(Ethylamino)ethanol

Conditions
ConditionsYield
With water at 25℃; anodic oxidation, pH 10, carbonate buffer; Further byproducts given;A 5%
B 72%
C 20%
D 73%
1120-64-5

2-methyl-4,5-dihydro-1,3-oxazole

110-73-6

2-(Ethylamino)ethanol

Conditions
ConditionsYield
With platinum on carbon; hydrogen at 25℃; under 30003 Torr; for 16h; Autoclave;60%
1120-64-5

2-methyl-4,5-dihydro-1,3-oxazole

A

110-73-6

2-(Ethylamino)ethanol

B

100-37-8

2-(Diethylamino)ethanol

Conditions
ConditionsYield
With platinum on carbon; hydrogen at 25℃; under 7500.75 Torr; for 16h;A 60%
B 19%
139-87-7

ethyldiethanolamine

110-73-6

2-(Ethylamino)ethanol

Conditions
ConditionsYield
With ethylamine In water at 350℃; for 2h; Temperature; Reagent/catalyst; Solvent;49.9%
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; caesium carbonate; ethylamine In water at 150℃; for 12h; Catalytic behavior; Reagent/catalyst; Temperature; Inert atmosphere;

2-(N-ethyltritylamino)ethanol

110-73-6

2-(Ethylamino)ethanol

Conditions
ConditionsYield
Stage #1: 2-(N-ethyltritylamino)ethanol With n-butyllithium In hexane at 0℃;
Stage #2: With naphthalene; lithium In tetrahydrofuran; hexane at 0℃; for 4.5h;
Stage #3: With water In tetrahydrofuran; hexane at 0 - 20℃;
41%
75-21-8

oxirane

75-04-7

ethylamine

A

139-87-7

ethyldiethanolamine

B

110-73-6

2-(Ethylamino)ethanol

110-86-1

pyridine

100-37-8

2-(Diethylamino)ethanol

94-36-0

dibenzoyl peroxide

A

75-07-0

acetaldehyde

B

109-89-7

diethylamine

C

110-73-6

2-(Ethylamino)ethanol

98069-33-1

ethyl-carbamic acid-(2-chloro-ethyl ester)

110-73-6

2-(Ethylamino)ethanol

Conditions
ConditionsYield
With sodium hydroxide und nachfolgendes Erwaermen auf 80-90grad;

2-(Ethylamino)ethanol Chemical Properties

IUPAC Name: 2-(Ethylamino)ethanol
The MF of 2-(Ethylamino)ethanol (110-73-6) is C4H11NO.

                          
The MW of 2-(Ethylamino)ethanol (110-73-6) is 89.14.
Synonyms of 2-(Ethylamino)ethanol (110-73-6): (2-Hydroxyethyl)ethylamine ; 2-(Ethylamino)-ethano ; 2-Ethylamino-1-ethanol ; 2-N-Monoethylaminoethanol ; Ethyl-2-hydroxyethylamine ; Monoethylaminoethanol ; Ethylaminoethanol,[combustibleliquidlabel] 
Product Categories: Alkohols
Form: Clear colorless to slightly yellowish liquid
Index of Refraction: 1.423  
EINECS: 203-797-5
Density: 0.883 g/ml 
Flash Point: 71.1 °C 
Boiling Point: 169.5 °C
Melting Point: -90 °C
Water Solubility: miscible
BRN: 635671

2-(Ethylamino)ethanol Production

It is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

2-(Ethylamino)ethanol Toxicity Data With Reference

1.    

skn-rbt 10 mg/24H open MLD

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 10 (1954),61.
2.    

eye-rbt 250 µg open SEV

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 10 (1954),61.
3.    

orl-rat LD50:1000 mg/kg

    FCTXAV    Food and Cosmetics Toxicology. 5 (1967),327.
4.    

ipr-rat LD50:1170 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 12 (1968),486.
5.    

skn-rbt LD50:360 mg/kg

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 10 (1954),61.
6.    

orl-mam LD50:1200 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 8 (1966),344.

2-(Ethylamino)ethanol Consensus Reports

Reported in EPA TSCA Inventory.

2-(Ethylamino)ethanol Safety Profile

Poison by skin contact. Moderately toxic by ingestion and intraperitoneal routes. A skin and severe eye irritant. Flammable when exposed to heat or flame; can react vigorously with oxidizers. To fight fire, use alcohol foam, dry chemical, CO2. When heated to decomposition it emits toxic fumes of NOx.
Safety information of 2-(Ethylamino)ethanol (110-73-6):
Hazard Codes  T
Risk Statements 
22  Harmful if swallowed
24  Toxic in contact with skin
41  Risk of serious damage to eyes
34  Causes burns
Safety Statements 
26  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39  Wear suitable protective clothing, gloves and eye/face protection
45  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR  UN 2810 6.1/PG 3
WGK Germany  1
RTECS  KK9100000
HazardClass  8
PackingGroup  III
HS Code  29221980

2-(Ethylamino)ethanol Specification

A colorless liquid with an amine-like odor. Flash point 160°F. Slightly less dense than water. May mildly irritate skin and eyes. At high temperature may decompose to yield toxic oxides of nitrogen.

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