Reported in EPA TSCA Inventory.

The β-Thiodiglycol, with the CAS registry number 111-48-8, is also known as 2,2'-Sulfanediyldiethanol. It belongs to the product category of Organics. Its EINECS registry number is 203-874-3. This chemical's molecular formula is C₄H₁₀O₂S and molecular weight is 122.19. What's more, its IUPAC name is called 2-(2-Hydroxyethylsulfanyl)ethanol. β-Thiodiglycol is a viscous, clear to pale-yellow liquid. It is used as a solvent in a variety of applications ranging from dyeing textiles to inks in some ballpoint pens. In chemical synthesis, the production is used as a building block for protection products, dispersants, fibers, plasticizers, rubber accelerators, pesticides, dyes, and various other organic chemicals. In the manufacture of polymers, this chemical is used as a chain transfer agent. As an antioxidant, it is used as an additive in lubricants.

Physical properties about β-Thiodiglycol are: (1)# of Rule of 5 Violations: 0; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 9.75; (5)ACD/KOC (pH 7.4): 9.75; (6)#H bond acceptors: 2; (7)#H bond donors: 2; (8)#Freely Rotating Bonds: 6; (9)Polar Surface Area: 65.76 Å²; (10)Index of Refraction: 1.523; (11)Molar Refractivity: 31.64 cm³; (12)Molar Volume: 103.5 cm³; (13)Surface Tension: 50 dyne/cm; (14)Density: 1.18 g/cm³; (15)Flash Point: 139.5 °C; (16)Enthalpy of Vaporization: 60.45 kJ/mol; (17)Boiling Point: 282 °C at 760 mmHg; (18)Vapour Pressure: 0.000407 mmHg at 25 °C.

Preparation of β-Thiodiglycol: this chemical can be prepared by Chlorohydrin with Sodium sulfide. This reaction needs reagent sulfuric acid at temperature of 90-95 °C.

2CH₂Cl-CH₂OH + Na₂S → (CH₂CH₂OH)₂S + 2NaCl

Uses of β-Thiodiglycol: it is used to produce other chemicals. For example, it can react with Methanol to get Bis-(2-methoxy-ethyl)-sulfane. The reaction occurs with reagent p-Toluenesulfonic acid monohydrate at temperature of 150 °C. The reaction time is 10 hours. The yield is 66 %.

When you are dealing with this chemical, you should be very careful. This chemical is inflammation to the skin, eyes and respiratory system or other mucous membranes. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. And in case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: OCCSCCO
(2) InChI: InChI=1S/C4H10O2S/c5-1-3-7-4-2-6/h5-6H,1-4H2
(3) InChIKey: YODZTKMDCQEPHD-UHFFFAOYSA-N

The toxicity data is as follows: