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2-Amino-4-chloro-6-methylpyrimidine

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Name

2-Amino-4-chloro-6-methylpyrimidine

EINECS 227-018-3
CAS No. 5600-21-5 Density 1.349 g/cm3
PSA 51.80000 LogP 1.60180
Solubility Insoluble in water. Melting Point 182-186 °C
Formula C5H6ClN3 Boiling Point 326 °C at 760 mmHg
Molecular Weight 143.576 Flash Point 151 °C
Transport Information N/A Appearance brown to light yellow powder
Safety 22-24/25-36/37/39-26 Risk Codes 36/37/38-20/21/22
Molecular Structure Molecular Structure of 5600-21-5 (2-Amino-4-chloro-6-methylpyrimidine) Hazard Symbols IrritantXi,HarmfulXn
Synonyms

Pyrimidine,2-amino-4-chloro-6-methyl- (6CI,7CI,8CI);2-Amino-4-chloro-6-methylpyrimidine;4-Chloro-6-methyl-2-pyrimidinamine;4-Chloro-6-methylpyrimidin-2-ylamine;AM;AM (nitrification inhibitor);NSC23661;NSC 7892;

Article Data 21

2-Amino-4-chloro-6-methylpyrimidine Standards and Recommendations

Assay: 98%

2-Amino-4-chloro-6-methylpyrimidine Specification

The 2-Amino-4-chloro-6-methylpyrimidine with the cas number 5600-21-5. It is also called (1)2-Pyrimidinamine, 4-chloro-6-methyl- (9CI) ; (2)4-Chloro-6-methylpyrimidin-2-ylamine ; (3)Pyrimidine, 2-amino-4-chloro-6-methyl- . It belongs to the following product categories: (1)Pyrimidine; (2)Fine Chemical&intermediates; (3)Fluorobenzene; (4)Amines; (5)Pyrazines, Pyrimidines & Pyridazines; (6)Pyrimidines; (7)Building Blocks; (8)Halogenated Heterocycles; (9)Heterocyclic Building Blocks; (10)PyrimidinesHeterocyclic Building Blocks.

Properties of 2-Amino-4-chloro-6-methylpyrimidine : (1)ACD/LogP: 0.75 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): 0.751 ; (4)ACD/LogD (pH 7.4): 0.753 ; (5)ACD/BCF (pH 5.5): 2.191 ; (6)ACD/BCF (pH 7.4): 2.199 ; (7)ACD/KOC (pH 5.5): 60.938 ; (8)ACD/KOC (pH 7.4): 61.184 ; (9)#H bond acceptors: 3 ; (10)#H bond donors: 2 ; (11)#Freely Rotating Bonds: 0 ; (12)Polar Surface Area: 51.8 Å2 ; (13)Index of Refraction: 1.6 ; (14)Molar Refractivity: 36.391 cm3 ; (15)Molar Volume: 106.387 cm3 ; (16)Polarizability: 14.427 ×10-24cm3 ; (17)Surface Tension: 59.053 dyne/cm ; (18)Density: 1.35 g/cm3 ; (19)Flash Point: 150.965 °C ; (20)Enthalpy of Vaporization: 56.818 kJ/mol ; (21)Boiling Point: 326.009 °C at 760 mmHg ; (22)Vapour Pressure: 0 mmHg at 25°C

The 2-Amino-4-hydroxy-6-methylpyrimidine seems like white to light yellow needle-like cryst powder. It is quite irritating to eyes, respiratory system and skin. When you are using this chemical, please wear suitable gloves and eye/face protection to avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, Do not breathe dust, because it is quite harmful by inhalation, in contact with skin and if swallowed.

The 2-Amino-4-hydroxy-6-methylpyrimidine can react with 3-bromo-2-oxo-propionic acid ethyl ester to obtained 5-chloro-7-methyl-imidazo[1,2-a]pyrimidine-2-carboxylic acid ethyl ester with heating for 48 hour(s). Yield is 48 % .



You can still convert the following datas into molecular structure :
1.SMILES:Cc1cc(nc(n1)N)Cl
2.InChI:InChI=1/C5H6ClN3/c1-3-2-4(6)9-5(7)8-3/h2H,1H3,(H2,7,8,9)

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