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Name |
2-Amino-4-chlorobenzoic acid |
EINECS | 201-938-5 |
CAS No. | 89-77-0 | Density | 1.476 g/cm3 |
PSA | 63.32000 | LogP | 2.20160 |
Solubility | slightly soluble in water | Melting Point |
231-233 °C(lit.) |
Formula | C7H6ClNO2 | Boiling Point | 351.2 °C at 760 mmHg |
Molecular Weight | 171.583 | Flash Point | 166.2 °C |
Transport Information | N/A | Appearance | off-white powder |
Safety | 26-36-37/39 | Risk Codes | 36/37/38-20/21/22 |
Molecular Structure | Hazard Symbols | Xn, Xi | |
Synonyms |
4-Chloroanthranil acid;2-amino-4-chlorobenzoic-acid;2-amino-4-chloro-benzoate;Anthranilic acid, 4-chloro-;4-Chloroanthranilic acid;4-14-00-01072 (Beilstein Handbook Reference);4-Chloro-2-Aminobenzoic acid;2-amino-4-chloro-benzoic acid;Anthranilic acid, 4-chloro- (6CI,7CI,8CI);Benzoic acid, 2-amino-4-chloro-; |
Article Data | 28 |
Conditions | Yield |
---|---|
With ammonium hydroxide at 126 - 129℃; under 3800 - 9120 Torr; for 6h; | 88% |
With ammonia; copper at 120℃; |
2,4-dichlorobenzoic acid potassium salt
2-Amino-4-chlorobenzoic acid
Conditions | Yield |
---|---|
With ammonium hydroxide; copper diacetate at 126 - 129℃; for 10h; | 68% |
Conditions | Yield |
---|---|
With tin(II) chloride dihdyrate In ethanol for 1h; Inert atmosphere; | 23% |
With platinum Hydrogenation; | |
With ammonia; iron(II) sulfate |
Conditions | Yield |
---|---|
With sodium hydroxide; dihydrogen peroxide |
Conditions | Yield |
---|---|
With sulfuric acid |
7-chloro-3-(3-chlorophenyl)quinazoline-2,4(1H,3H)-dione
2-Amino-4-chlorobenzoic acid
Conditions | Yield |
---|---|
With potassium hydroxide |
4-chlorophthalamide
2-Amino-4-chlorobenzoic acid
Conditions | Yield |
---|---|
With alkaline aqueous potassium hypobromite |
Conditions | Yield |
---|---|
With hydrogenchloride Zers. des entstandenen Hydrochlorids mit Natriumacetat; |
methanol
6-chloroisatin
A
2-amino-4-chloro-benzoic acid methyl ester
B
2-Amino-4-chlorobenzoic acid
Conditions | Yield |
---|---|
With dihydrogen peroxide; sodium methylate 1.) 0-10 deg C 2.) room temperature, 30 min; Yield given. Multistep reaction; |
The Molecular formula of 2-Amino-4-chlorobenzoic acid(89-77-0) : C7H6ClNO2
The Molecular Weight of 2-Amino-4-chlorobenzoic acid(89-77-0): 171.58
Molecular Structure :
Melting point: 231-235 oC
WATER solubility: slightly soluble
Appearance: White or yellowish crystal
2-Amino-4-chlorobenzoic acid(89-77-0) is a intermediate for pharmaceuticals, and other organic products
Irritating to eyes, respiratory system and skin.The toxicological properties of 2-Amino-4-chlorobenzoic acid(89-77-0) have not been fully investigated.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation: May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema.
The Hazard Codes of 2-Amino-4-chlorobenzoic acid(89-77-0) : Xi
The Risk Statements information of 2-Amino-4-chlorobenzoic acid(89-77-0) :
36/37/38: Irritating to eyes, respiratory system and skin
The Safety Statements information of 2-Amino-4-chlorobenzoic acid(89-77-0):
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
37/39: Wear suitable gloves and eye/face protection