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Cas Database |
| Name |
2-Amino-4-nitro anisidine |
EINECS | 202-770-5 |
| CAS No. | 99-59-2 | Density | 1.318 g/cm3 |
| PSA | 81.07000 | LogP | 2.29000 |
| Solubility | Slightly soluble in water: <0.01 g/100 mL at 19.5 °C | Melting Point |
117-119 °C(lit.) |
| Formula | C7H8N2O3 | Boiling Point | 351.794 °C at 760 mmHg |
| Molecular Weight | 168.152 | Flash Point | 166.559 °C |
| Transport Information | N/A | Appearance | orange to brown powder |
| Safety | 26-36-45-36/37 | Risk Codes | 36/37/38-20/21/22 |
| Molecular Structure |
|
Hazard Symbols |
 Xi, Xn
|
| Synonyms |
o-Anisidine,5-nitro- (8CI);(2-Methoxy-5-nitrophenyl)amine;1-Amino-2-methoxy-5-nitrobenzene;1-Methoxy-2-amino-4-nitrobenzene;2-(Methyloxy)-5-nitroaniline;2-Amino-1-methoxy-4-nitrobenzene;2-Amino-4-nitroanisole;2-Methoxy-5-nitroaniline;2-Methoxy-5-nitrobenzenamine;3-Nitro-6-methoxyaniline;4-Nitro-2-aminoanisole;5-Nitro-2-methoxyaniline;5-Nitro-o-anisidine;Azoamine Scarlet K;NSC 5510; |
Article Data | 40 |
2-Amino-4-nitro anisidine Chemical Properties
IUPAC Name: 2-Methoxy-5-nitroaniline
The molecular formula of 5-Nitro-o-anisidine (CAS NO.99-59-2) is C7H8N2O3.
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The molecular weight of 5-Nitro-o-anisidine (CAS NO.99-59-2) is 168.150020.
Synonyms of 5-Nitro-o-anisidine (CAS NO.99-59-2): 1-Amino-2-methoxy-5-nitrobenzene ; 1-Methoxy-2-amino-4-nitrobenzene ; 2-Methoxy-5-nitro-anilin ; 2-Methoxy-5-nitrobenzamine ; 2-Methoxy-5-nitro-benzenamin
Product Categories: Intermediates of Dyes and Pigments
Stability: Stable, but may be moisture sensitive. Incompatible with water, acids, strong oxidizing agents, acid chlorides, acid anhydrides, chloroformates
Apperance: orange to brown powder
Melting Point: 117-119 °C
Density: 1.2068
Colour Index: 37130
Water Solubility: Slightly soluble
BRN: 879620
EINECS: 202-770-5
2-Amino-4-nitro anisidine Uses
5-Nitro-o-anisidine (CAS NO.99-59-2) is used as a dye, pigment and organic synthesis intermediates.
2-Amino-4-nitro anisidine Production
Derived from 2,4-Dinitrochlorobenzene by the reaction of methoxy and restore.
2-Amino-4-nitro anisidine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 1060mg/kg (1060mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(8), Pg. 50, 1981. | |
| rabbit | LD50 | oral | 1gm/kg (1000mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(3), Pg. 48, 1988. | |
| rat | LD50 | oral | 2250mg/kg (2250mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(3), Pg. 48, 1988. |
2-Amino-4-nitro anisidine Consensus Reports
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 ,1982,p. 133.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); Clear Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-127 ,1978. . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program. Community Right-To-Know List.
2-Amino-4-nitro anisidine Safety Profile
Suspected carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS of AROMATIC HYDROCARBONS.Safety information of 5-Nitro-o-anisidine (CAS NO.99-59-2):
Hazard Codes 
Xi,Xn
Risk Statements 36/37/38-20/21/22
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-45-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany 2
RTECS BZ7175000
Hazard Note Irritant
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