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2-Chloro-5-nitrobenzaldehyde

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Name

2-Chloro-5-nitrobenzaldehyde

EINECS 228-830-0
CAS No. 6361-21-3 Density 1.485 g/cm3
PSA 62.89000 LogP 2.58390
Solubility N/A Melting Point 75-77 °C(lit.)
Formula C7H4ClNO3 Boiling Point 290.3 °C at 760 mmHg
Molecular Weight 185.567 Flash Point 129.4 °C
Transport Information N/A Appearance light yellow to beige-yellow crystalline powder
Safety 22-24/25-37/39-26-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 6361-21-3 (2-Chloro-5-nitrobenzaldehyde) Hazard Symbols IrritantXi
Synonyms

3-Nitro-6-chlorobenzaldehyde;5-Nitro-2-chlorobenzaldehyde;6-Chloro-3-nitrobenzaldehyde;NSC 129753;

Article Data 14

2-Chloro-5-nitrobenzaldehyde Chemical Properties

Chemical Name: 2-Chloro-5-nitrobenzaldehyde                          
IUPAC NAME: 2-chloro-5-nitrobenzaldehyde                                  
CAS No.: 6361-21-3
EINECS: 228-830-0
RTECS: CU5220000
Molecular Formula: C7H4ClNO3
Molecular Weight: 185.56 g/mol
Polar Surface Area: 62.89 Å2
Index of Refraction: 1.63
Molar Refractivity: 44.44 cm3
Molar Volume: 124.8 cm3
Surface Tension: 57.3 dyne/cm
Enthalpy of Vaporization: 52.97 kJ/mol
Vapour Pressure: 0.00209 mmHg at 25°C
Density: 1.485 g/cm3
Flash Point: 129.4 °C
Boiling Point: 75-77 °C(lit.)
 2-Chloro-5-nitrobenzaldehyde is stable under normal temperatures and pressures.it is off white to light yellow powder and air sensitive but insoluble in water,incompatible with oxidizing agents,strong bases.
Following is the structure:

                    
The chemical synonymous of 2-Chloro-5-nitrobenzaldehyde (CAS NO.6361-21-3) are 3-Nitro-6-chlorobenzaldehyde
4-07-00-00609 (Beilstein Handbook Reference) ; BRN 0743764 ; EINECS 228-830-0 ; NSC 129753 ; Benzaldehyde, 2-chloro-5-nitro-                            
Product Categories are Carbonyl Compounds ; Aromatic Aldehydes & Derivatives (substituted) ; Benzaldehyde ; Aldehydes ; C7 ; Carbonyl Compounds             

2-Chloro-5-nitrobenzaldehyde Uses

    2-Chloro-5-nitrobenzaldehyde (CAS NO.6361-21-3) is mainly used as intermediates in organic synthesis.

2-Chloro-5-nitrobenzaldehyde Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 56mg/kg (56mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00052,
mouse LDLo oral 3200mg/kg (3200mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) National Technical Information Service. Vol. OTS0555310,
rat LD50 oral > 3200mg/kg (3200mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) National Technical Information Service. Vol. OTS0555310,

2-Chloro-5-nitrobenzaldehyde Consensus Reports

Reported in EPA TSCA Inventory.

2-Chloro-5-nitrobenzaldehyde Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/37/38 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-37/39-26-36 
S22: Do not breathe dust. 
S24/25: Avoid contact with skin and eyes. 
S37/39: Wear suitable gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36: Wear suitable protective clothing.
WGK Germany: 2
RTECS: CU5220000
F: 10
Hazard Note: Irritant/Air Sensitive
TSCA: T
A poison by intravenous route. When heated to decomposition it emits toxic vapors of NOx and Cl.

2-Chloro-5-nitrobenzaldehyde Specification

1. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
2. Handling: Avoid ingestion and inhalation.Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
3. Personal Protection: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
4. Fire Fighting: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

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