Benzenamine,2-chloro-

The 2-Chloroaniline, with the cas registry number 95-51-2, is a kind of clear pale yellow to brown liquid, with ammoniacal odour. This is insoluble in water while soluble in acid and other common organic solvents. Its product categories are various, including intermediates of dyes and pigments; anilines, aromatic amines and nitro compounds; organics; amines; c2 to c6; nitrogen compounds; alpha sort; c; calphabetic; ch; volatiles/ semivolatiles; aromaticspesticides&metabolites; chemical class.

The characteristics of this chemical are as follows: (1)ACD/LogP: 1.91; (2)ACD/LogD (pH 5.5): 1.91; (3)ACD/LogD (pH 7.4): 1.91; (4)ACD/BCF (pH 5.5): 16.62; (5)ACD/BCF (pH 7.4): 16.64; (6)ACD/KOC (pH 5.5): 260.11; (7)ACD/KOC (pH 7.4): 260.48; (8)#H bond acceptors: 1; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 1; (11)Polar Surface Area: 26.02; (12)Index of Refraction: 1.598; (13)Molar Refractivity: 35.38 cm³; (14)Molar Volume: 103.6 cm³; (15)Polarizability: 14.02 ×10^-24 cm³; (16)Surface Tension: 45.3 dyne/cm; (17)Density: 1.23 g/cm³; (18)Flash Point: 74.8 °C; (19)Enthalpy of Vaporization: 44.51 kJ/mol; (20)Boiling Point: 208.8 °C at 760 mmHg; (21)Vapour Pressure: 0.209 mmHg at 25°C.

Production method of 2-Chloroaniline is as below: 1-chloro-2-nitro-benzene could react to produce 2-Chloroaniline, with the following condition: solvent: ammonium formate; reaction time: 45 min; reaction tem.: 20 ℃; yield: 90%.

Use of 2-Chloroaniline: 2-Chloroaniline reacts with maleic acid anhydride to produce N-(2-chloro-phenyl)-maleamic acid, with the following condition: solvent: benzene; reaction time: 30 min; yield: 92% chromat; other condition: ambient temperature.

As to its usage, it is widely applied in many ways. It could be used in producing acid black, acid blue, permanent bordeaux FR, ARPermanent YellowAR R, Hansa yellow HR and so on; It could be used in producing the cross-linking agent methyldichloroaniline in pharmaceutic, pesticide and polyurethane resin; It could be used as the intermediate of dye and pesticide.

While dealing with this chemical, you should be very cautious. For onet thing, this chemical is toxic and will at low levels cause damage to health; If through inhalation, in contact with skin and if swallowed, it will have very serious irreversible effects. For another thing, it is dangerous for the environment and may present an immediate or delayed danger to one or more components of the environment; It is also toxic to aquatic organisms and may cause long-term adverse effects in the aquatic environment; Then, it is highly flammable. It may catch fire in contact with air, only needing brief contact with an ignition source, and it has a very low flash point or evolve highly flammable gases in contact with water. You should take the following instructions. Wear suitable protective clothing and gloves, and if in case of accident or if you feel unwell, seek medical advice immediately (show the label where possible); After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer); While keeping it, this material and its container must be disposed of as hazardous waste; Then avoid release to the environment and refer to special instructions/safety data sheet.

Additionally, the following datas could be converted into the molecular structure:
SMILES:Nc1ccccc1Cl

Below are the toxicity informatin of this chemical: