Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
2-Dimethylamino-2-Methyl-1-Propanol |
EINECS | N/A |
CAS No. | 7005-47-2 | Density | 0.95g/mLat 20°C(lit.) |
PSA | 23.47000 | LogP | 0.31890 |
Solubility | 1000g/L at 20℃ | Melting Point |
19°C |
Formula | C6H15 N O | Boiling Point | 61°C20mm Hg |
Molecular Weight | 117.191 | Flash Point | 145°F |
Transport Information | N/A | Appearance | N/A |
Safety | Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | 34-35 |
Molecular Structure | Hazard Symbols | C | |
Synonyms |
2-(Dimethylamino)-2-methyl-1-propanol;2-(Dimethylamino)-2-methylpropyl alcohol;2-(N,N-Dimethylamino)-2-methyl-1-propanol; DMAMP; DMAMP 80;N,N-Dimethyl-2-amino-2-methylpropan-1-ol; NSC 17706; T-Amine WR 500 |
Article Data | 11 |
Conditions | Yield |
---|---|
With formic acid at 80℃; for 24h; | 46% |
With formic acid; water | |
With titanium(IV) isopropylate; sodium tetrahydroborate 1.) diglyme, 60 deg C, 30 min then r.t., 30 min; 2.) diglyme, r.t., 3 h then 60 deg C, 3 h; Yield given. Multistep reaction; | |
With sodium tetrahydroborate; zinc(II) chloride 1.) CH2Cl2, RT, 1 h, 2.) CH2Cl2, 11 h; Yield given. Multistep reaction; | |
Stage #1: formaldehyd; 2-Amino-2-methyl-1-propanol With formic acid In water at 0 - 90℃; for 5h; Stage #2: With sodium hydroxide; water pH=14; |
Conditions | Yield |
---|---|
(methylation); |
Conditions | Yield |
---|---|
Stage #1: 2-nitro-2-methylpropanol With hydrogen Stage #2: formaldehyd | |
With hydrogen In methanol at 100℃; Autoclave; |
Conditions | Yield |
---|---|
In benzene at 60℃; | 100% |
In benzene at 60℃; | 28.3 g |
2-dimethylamino-2-methylpropan-1-ol
methyl iodide
2-(1-hydroxy-2-methyl)propyltrimethylammonium iodide
Conditions | Yield |
---|---|
In isopropyl alcohol at 20 - 45℃; for 4h; Inert atmosphere; | 94% |
2-dimethylamino-2-methylpropan-1-ol
sodium thiocyanide
copper(II) acetate monohydrate
[Cu((CH3)4NCCH2O)(NCS)]2
Conditions | Yield |
---|---|
In methanol MeOH soln. of NaNCS was added to MeOH soln. of Cu(OAc)2*H2O and ligand, allowed to stand at 25°C for several ds; filtered, dried in vacuo; elem. anal.; | 90% |
Conditions | Yield |
---|---|
In methanol MeOH soln. of CuCl2 was added to MeOH soln. of ligand, allowed to stand at 25°C for several ds; filtered, dried in vacuo; elem. anal.; | 90% |
2-dimethylamino-2-methylpropan-1-ol
benzo[b]thiophene-3-carbonyl azide
Conditions | Yield |
---|---|
In benzene Heating; | 80% |
N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-fluoro-6-nitroquinazolin-4-amine
2-dimethylamino-2-methylpropan-1-ol
Conditions | Yield |
---|---|
With potassium tert-butylate In dimethyl sulfoxide at 25℃; for 2h; | 77% |
benzothiophene-3-carbonyl chloride
2-dimethylamino-2-methylpropan-1-ol
Conditions | Yield |
---|---|
In benzene Heating; | 70% |
Chemistry informtion about 2-Dimethylamino-2-Methyl-1-Propanol (CAS NO.7005-47-2) is:
IUPAC Name: 2-(Dimethylamino)-2-Methylpropan-1-Ol
Synonyms: Dmamp-80(Tm) ; 2-(N,N-Dimethylamino)Isobutanol ; 2-Dimethylaminoisobutanol ; 2-Dimethylamino-2-Methyl-1-Propanol ; 2-(Dimethylamino)-2-Methyl-1-Propano ; 2-(Dimethylamino)-2-Methylpropanol ; 2-(N,N-Dimethylamino)-2-Methyl-1-Propanol ; 2-Dimethylamino-2-Methyl-1-Propano
MF: C6H15NO
MW: 117.19
EINECS: 230-279-6
Density: 0.885 g/cm3
Flash Point: 39.9 °C
Boiling Point: 151 °C at 760 mmHg
Vapour Pressure: 1.41 mmHg at 25°C
Enthalpy of Vaporization: 45.18 kJ/mol
Refractive Index: n20/D 1.447
Following is the molecular structure of 2-Dimethylamino-2-Methyl-1-Propanol (CAS NO.7005-47-2) is:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 25mg/kg (25mg/kg) | National Technical Information Service. Vol. AD277-689, |
Reported in EPA TSCA Inventory.
Safty information about 2-Dimethylamino-2-Methyl-1-Propanol (CAS NO.7005-47-2) is:
Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
C
Risk Statements:
R34:Causes burns.
Safety Statements:
S23:Do not breathe vapour.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2735 8/PG 3
RTECS: UB3325000
F:
F 10: Keep under argon.
F 34: Sensitive to CO2.
HazardClass: 3.2
PackingGroup: III