2-Fluoroadenosine (146-78-1),2-Fluoroadenosine (146-78-1) Manufacturers & Suppliers,Synthesis,MSDS

Basic information

Name:
Adenosine, 2-fluoro-
Superlist Name:
2-Fluoroadenosine
CAS No.:
146-78-1
Molecular Structure:
Formula:
C₁₀H₁₂FN₅O₄
Molecular Weight:
285.24 .
Synonyms:
2-Fluoro-9-b-D-ribofuranosyladenine;NSC 30605;
Density:
2.17 g/cm³
Melting Point:
240 °C
Boiling Point:
747.3 °C at 760 mmHg
Flash Point:
405.8 °C
Hazard Symbols:
Xn
Risk Codes:
22-36/37/38
Safety Description:
26 Details

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Chemistry

Chemical Name: 2-Fluoroadenosine
CAS No.: 146-78-1
IUPAC NAME: (2R,3R,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Molecular Formula: C₁₀H₁₂FN₅O₄
SMILES: Fc1nc(c2ncn(c2n1)C3OC(C(O)C3O)CO)N
Molecular Weight: 285.23 g/mol
Structure：

The synonyms of 2-Fluoroadenosine(146-78-1): 2-far;2-fas; 2-fluoro-adenosin; 6-amino-2-fluoro-9-beta-d-ribofuranosyl-purin; 6-amino-2-fluoro-9-beta-d-ibofuranosylpurine; 2-FLUOROADENOSINE; 2-FLUOROADENOSINE(FLUDARABINE INTERMEDIATE)
Density: 2.17 g/cm³
Flash Point: 405.8 °C
Boiling Point: 747.3 °C at 760 mmHg

Production

Product Categories: Miscellaneous Biochemicals; API intermediates; Biochemistry; Nucleosides and their analogs; Nucleosides, Nucleotides & Related Reagents; Nucleosides; Oligonucleotide Synthesis; Specialty Synthesis

Toxicity Data With Reference

mouse LD10 unreported 1000ug/kg (1mg/kg) Progress in Medical Chemistry. Vol. 7, Pg. 69, 1970.

mouse LD50 intraperitoneal 27040ug/kg (27.04mg/kg) National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,

Safety Profile

Hazard Codes:
    Xn:   Harmful
Risk Statements about 2-Fluoroadenosine(146-78-1):
    R22 Harmful if swallowed.
    R36/37/38 Irritating to eyes, respiratory system and skin.
Safety Statements about 2-Fluoroadenosine(146-78-1):
    S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical
advice.