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| Name |
2-Hydroxypropyl-beta-cyclodextrin |
EINECS | 420-920-1 |
| CAS No. | 128446-35-5 | Density | 1.05 at 20.3℃ |
| PSA | 618.66000 | LogP | -12.39490 |
| Solubility | Soluble in water. | Melting Point |
278oC (dec.) |
| Formula | Unspecified | Boiling Point | 400℃ |
| Molecular Weight | 1541.54000 | Flash Point | N/A |
| Transport Information | N/A | Appearance | white powder |
| Safety | 24/25 | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Hydroxypropyl-beta-cyclodextrin; |
2-Hydroxypropyl-beta-cyclodextrin Synthetic route
- 33069-62-4
taxol
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
| Conditions | Yield |
|---|---|
| In ethanol at 30℃; for 24h; |
- 2224-15-9
ethylene glycol diglycidyl ether
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
| Conditions | Yield |
|---|---|
| In sodium hydroxide at 20 - 50℃; |
- 14252-80-3, 15233-43-9, 18010-40-7, 27262-46-0, 27262-48-2
bupivacaine hydrochloride
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
| Conditions | Yield |
|---|---|
| In water-d2 |
- 80-12-6
Tetramethylenedisulfotetramine
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
| Conditions | Yield |
|---|---|
| In water-d2 at 30℃; |
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
- 132203-70-4
cilnidipine
| Conditions | Yield |
|---|---|
| In water at 20℃; for 24h; |
- 144701-48-4
telmisatran
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
| Conditions | Yield |
|---|---|
| In water at 37℃; for 24h; pH=10; |
- 151319-34-5
zaleplon
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
| Conditions | Yield |
|---|---|
| In water-d2 at 21.84℃; Thermodynamic data; |
- 80-05-7
BPA
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
| Conditions | Yield |
|---|---|
| With hydrogenchloride In water at 20℃; |
- 1806-26-4
p-Octylphenol
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
| Conditions | Yield |
|---|---|
| With hydrogenchloride In water at 20℃; |
- 104-40-5
4-Nonylphenol
- 128446-35-5
heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
| Conditions | Yield |
|---|---|
| With hydrogenchloride In water at 20℃; |
2-Hydroxypropyl-beta-cyclodextrin Chemical Properties
Molecule structure of 2-Hydroxypropyl-beta-cyclodextrin (CAS NO.128446-35-5):
Molecular Formula: C42.(H)70-n.O35.(C3H7)n
Melting Point: 278 °C (dec.)
Refractive Index: 125 ° (C=1, H2O)
Storage Temp.: 2-8 °C
Water Solubility: 45 % (w/v)
Appearance: white to slightly yellow powder
EINECS: 420-920-1
Product Categories of 2-Hydroxypropyl-beta-cyclodextrin (CAS NO.128446-35-5): Biochemistry; Cyclodextrins; Functional Materials; Macrocycles for Host-Guest Chemistry; Oligosaccharides; Sugars; Chelation/Complexation Compounds; Synthetic Reagents; CyclodextrinsCell Culture; CyclodextrinsSynthetic Reagents; Cell Signaling and Neuroscience; Lipids and Lipid Carriers; Reagents and Supplements; Signal Transduction Research Tools
2-Hydroxypropyl-beta-cyclodextrin Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD | intravenous | > 5gm/kg (5000mg/kg) | Journal of Pharmaceutical Sciences. Vol. 84, Pg. 1223, 1995. |
2-Hydroxypropyl-beta-cyclodextrin Safety Profile
WGK Germany: 3
RTECS: GU2293332
2-Hydroxypropyl-beta-cyclodextrin Specification
2-Hydroxypropyl-beta-cyclodextrin (CAS NO.128446-35-5) is also named as HPB ; UNII-1I96OHX6EK ; beta-Hydroxypropylcyclodextrin ; beta-Cyclodextrin, 2-hydroxypropyl ether ; Hydroxypropyl-beta-cyclodextrin .
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