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2-Naphthalenecarboxylicacid, hydrazide

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Name

2-Naphthalenecarboxylicacid, hydrazide

EINECS 254-547-7
CAS No. 39627-84-4 Density 1.232 g/cm3
PSA 55.12000 LogP 2.53450
Solubility N/A Melting Point 146-148 °C
Formula C11H10N2O Boiling Point 302-304°C 725mm
Molecular Weight 186.213 Flash Point 302-304°C/725mm
Transport Information N/A Appearance N/A
Safety 26-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 39627-84-4 (2-NAPHTHHYDRAZIDE) Hazard Symbols IrritantXi
Synonyms

2-Naphthohydrazide;

Article Data 38

2-Naphthalenecarboxylicacid, hydrazide Specification

The 2-Naphthalenecarboxylicacid, hydrazide, with the CAS registry number of 39627-84-4, is also known as 2-Naphthohydrazide. It belongs to the product categories of Aromatic Hydrazides; Hydrazines; Hydrazones and Oximes. Its EINECS registry number is 254-547-7. Its molecular formula is C11H10N2O and molecular weight is 186.21. What's more, its IUPAC name is Naphthalene-2-carbohydrazide. In addition, it must be stored in airtight containers and placed in a dry, cool place.

Physical properties about the 2-Naphthalenecarboxylicacid, hydrazide are: (1)ACD/LogP: 1.48; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.48; (4)ACD/LogD (pH 7.4): 1.48; (5)ACD/BCF (pH 5.5): 7.8; (6)ACD/BCF (pH 7.4): 7.81; (7)ACD/KOC (pH 5.5): 151.28; (8)ACD/KOC (pH 7.4): 151.58; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 23.55 Å2; (13)Index of Refraction: 1.672; (14)Molar Refractivity: 56.62 cm3; (15)Molar Volume: 151 cm3; (16)Surface Tension: 56.1 dyne/cm; (17)Density: 1.232 g/cm3.

Preparation: this chemical can be obtained by Naphthalene-2-carboxylic acid methyl ester. The reaction needs reagent Hydrazine hydrate. The reaction time is 5 h. The yield is about 71 %.

The 2-Naphthalenecarboxylicacid, hydrazide can be obtained by Naphthalene-2-carboxylic acid methyl ester  

Uses: it is used to produce other chemicals. For example, it is used to produce 1,2-Dihydro-benzo[f]indazol-3-one. This reaction needs reagent n-BuLi. Meanwhile, it needs solvent Tetrahydrofuran. The reaction time is 1.5 h with reaction temperature of -78 °C. The yield is about 11 %.

The 2-Naphthalenecarboxylicacid, hydrazide is used to produce 1,2-Dihydro-benzo[f]indazol-3-one

When you are using this chemical, please be cautious about it as the following:
As a chemical, it is irritating to eyes, respiratory system and skin. If contact with eyes accidently, rinse immediately with plenty of water and seek medical advice. In addition, during using it, wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(NN)c2ccc1c(cccc1)c2
(2) InChI: InChI=1/C11H10N2O/c12-13-11(14)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,12H2,(H,13,14)
(3) InChIKey: RARLPRMZJNIQGU-UHFFFAOYAF

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