Basic Information | Post buying leads | Suppliers |
Name |
3-[2-[[(2-Methoxyphenyl)methyl]amino]ethyl]-2,4(1H,3H)-quinazolinedione |
EINECS | N/A |
CAS No. | 1028307-48-3 | Density | 1.232 |
PSA | 76.38000 | LogP | 2.29140 |
Solubility | N/A | Melting Point |
N/A |
Formula | C18H19N3O3 | Boiling Point | N/A |
Molecular Weight | 325.36 | Flash Point | N/A |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
3-{2-[(2-Methoxybenzyl)amino]ethyl}-2,4(1H,3H)-quinazolinedione; 3-[2-[[(2-Methoxyphenyl)methyl]amino]ethyl]-2,4(1H,3H)-quinazolinedione; 3-[2-[[(2-Methoxyphenyl)Methyl]Amino]Ethyl]-2,4(1H,3H)Quinazolinedione |
RH-34 is a compound which acts as a potent and selective partial agonist for the 5-HT2A serotonin receptor subtype. It was derived by structural modification of the selective 5-HT2A antagonist ketanserin, with the 4-(p-fluorobenzoyl)piperidine moiety replaced by the N-(2-methoxybenzyl) pharmacophore found in such potent 5-HT2A agonists as NBOMe-2C-B and NBOMe-2C-I. This alteration was found to retain 5-HT2A affinity and selectivity, but reversed activity from an antagonist to a moderate efficacy partial agonist.